Organic Affective disorder Flashcards
What is the triadic diagnostic System of Mental disorders?
First layer: Organic cause
Second layer: Endogenous Psychiatric Disorder (Psychoses)
Third layer: Exogenous: psychosocial experience
Not explicit in DSM-5 and icd, but implicit in mood disorders and hierarchy vs adjustment disorders
What mental disorders could we fit into the triadic disgnistic system?
Organic: Affective disorders
Endogenous (subtle organic): Bi-polar and MDD
Exogenous (No organic): Adjustment Disorder
What are the 4 criteria for Organic Mental Disorder to be considered according to the ICD?
1: There is evidence of or history of psychiatric/cerebreal disorder without psychoactive
2: Relationship of organic cause and disorder developing
3: recovery or improvement of disorder is linked to organic removal or improvement
4: Absence of sufficient evidence of alternative answer
1,2, 4 needed for provisional diagnosis
3 cements diagnosis is certain
How does the DSM 5 represent organic mood disorders?
Under classification of Mood Disorder due to another medical condition: All 5 criteria must be met.
Mood disorder criteria
Direct relationship with pahtophyisology
Not better explained by another mental disorder
Not apparent only during delirium
Causes distress
What is the relationship between Parkinsons and depression?
Parkinsons affects a dopamieric system related to movement, but not necessarily reward systems
50-70% of Parkinsons patients are depressed
Depression or anxiety may precede Parkinsons
Depressive patients are 3 x more at risk of parkinsons.
What is the relationship between strokes and depression?
Over half of stroke patents suffer from Depression.
Most common in left hemisphere stroke
White matter damage near striatum and insula
Stoke disrupts network hypothesis
What Is the hypothesis of white matter disruption based on?
Stroke patients and head trauma.
Using DTI even mild head trauma show white matter disruption similar to depression
What is the relationship between epilepsy and mood disorders?
Pre-Ictal (before seizure) : Depressed mood, return to normal after seizure.
Inter-Ictal: (2/3 patients)
MDD, dysthymia, irritability, bi-polar symptoms
What are some organic causes to mood disorders?
Parkinson's Head trauma Stroke Epilepsy Dementia Tumor
How can Hypercortisolism effect mood disorder?
Hypercortolism = Cushing syndrome-can be caused by endognenous cortisol excess or exogenoneous from piturity tumor
Psychiatric disorders linked are:
Mainia (minority) Irratiabity (86%) MDD (57%) Depressed mood (74%) Anxiety and Panic (66%)
How does thyroid dysfunction effect mood disorders?
Hyperthyroidism
Anxiety 60%
Depressive disorder 30-60%
Hypothyroidism:
Depression like symptoms
Depression
Visual hallucinations
Mood disorders not usually linked, but present as depression
How can Poly ovary Syst effect disorders?
24/36 patients meet criteria for one form of mental health condition.
How does vitamin defiecncy effect mood?
Folic acid is made into chemicals for our body, SAM-E is used to convert it and seems to affect mood.
Deficnieny in Folic acid is related to depression, b-12 metabolism is related so both need to be checked.
What are the DSM criteria of substance induced mood disorders?
Meet mood disorder ctiteria
Evidence that:
Symptoms occur after use
Substance is capable of causing it
Not better explained by another mood disorder
Not just during Delirium
Significant distress
All of the above
What does the small number of mania episodes when using drugs suggest about their role?
That the role may not be causal
