Organ Function Tests - Flashcards
What do OFTs Monitor?
typically plasma proteins or protein degradation products
what can a change in plasma protein conc. indicate generally?
- trauma
- drug toxicity
- Infection
- Tumour growth
- Organ damage
what is Troponin and how is it important to Cardiac function tests?
Troponin is a protein released into the bloodstream when heart muscle is damaged
- hs-cTnI or hs-cTnT troponin blood tests detect their levels and indicate the severity of damage
What Pathologies can be Diagnosed by a ‘Simple Blood Test’?
How can liver and thyroid function tests diagnose CVD?
a lipid profile will measure cholesterol levels (LDL, HDL, and lipoprotein). elevated LDL levels = risk of atherosclerosis and heart attack
Unstable Angina: Symptoms, diagnosis, and treatments
Myocardial Infarction (MI) – NSTEMI: Symptoms, diagnosis, and treatments
Myocardial Infarction (MI) – STEMI: Symptoms, diagnosis, and treatments
End-Stage Heart Failure: Symptoms, diagnosis, and treatments
B-Type (Brain) Natriuretic Peptide (BNP) Test
What is BNP?
hormone that helps to regulate blood volume (along with ANP)
What is NT-proBNP?
an inactive form of BNP released at the same time
what are the parameters of a liver function test (LFT)?
What are the most common LFTs?
Serum albumin and clotting time (PTT/aPT/INR)
Serum bilirubin (Bil/gBil)
Serum enzyme activities:
Alkaline phosphatase (ALP)
Gamma-glutamyl transferase (GGT)
Aspartate aminotransferase (AST)
Alanine amino transferase (ALT)
what are the diagnostic liver enzymes
What is ALP? what are the adult reference ranges?
Alkaline phosphate
What is GGT? what are the adult reference ranges?
What is AST? what are the adult reference ranges?
What is ALT? what are the adult reference ranges?
What liver enzyme measurements can you expect from athletes?
what does low albumin levels suggest and why?
chronic liver failure
albumin levels only decline after a few months
what is a myocardinal infarction caused by?
hypoxia, ischaemia, atherosclerosis
large eleva
