Organ Function Tests - Flashcards
What do OFTs Monitor?
typically plasma proteins or protein degradation products
what can a change in plasma protein conc. indicate generally?
- trauma
- drug toxicity
- Infection
- Tumour growth
- Organ damage
what is Troponin and how is it important to Cardiac function tests?
Troponin is a protein released into the bloodstream when heart muscle is damaged
- hs-cTnI or hs-cTnT troponin blood tests detect their levels and indicate the severity of damage
What Pathologies can be Diagnosed by a ‘Simple Blood Test’?
How can liver and thyroid function tests diagnose CVD?
a lipid profile will measure cholesterol levels (LDL, HDL, and lipoprotein). elevated LDL levels = risk of atherosclerosis and heart attack
Unstable Angina: Symptoms, diagnosis, and treatments
Myocardial Infarction (MI) – NSTEMI: Symptoms, diagnosis, and treatments
Myocardial Infarction (MI) – STEMI: Symptoms, diagnosis, and treatments
End-Stage Heart Failure: Symptoms, diagnosis, and treatments
B-Type (Brain) Natriuretic Peptide (BNP) Test
What is BNP?
hormone that helps to regulate blood volume (along with ANP)
What is NT-proBNP?
an inactive form of BNP released at the same time
what are the parameters of a liver function test (LFT)?
What are the most common LFTs?
Serum albumin and clotting time (PTT/aPT/INR)
Serum bilirubin (Bil/gBil)
Serum enzyme activities:
Alkaline phosphatase (ALP)
Gamma-glutamyl transferase (GGT)
Aspartate aminotransferase (AST)
Alanine amino transferase (ALT)
what are the diagnostic liver enzymes
