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Special Diagnostic Procedures > Organ Donation > Flashcards

Organ Donation Flashcards

1
Q

Organ donation is a process of ______________________

A

removing tissues or organs from a live, or recently dead/deceased, person to be used in another

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2
Q

What are the vital organs that can be successfully transplanted?

A

kidney, liver, heart, lungs, small intestines

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3
Q

This refers to an individual who voluntarily donates organ, tissue, or part thereof, gratuitously to another who accepts it

A

Donor

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4
Q

This is an individual who received the organ or tissue through transplantation

A

Recipient

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5
Q

What are the three possible recipients?

A

Accredited medical/dental school college university
Tissue bank storage facility
Individual

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6
Q

What does PhilNOS stands for?

A

Philippine Network for Organ Sharing

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7
Q

When was PhilNOS established?

A

June 23, 2010

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8
Q

PhilNOS acts primarily as ____________

A

central coordinating body for organ donation/transplantation. They are responsible for allocation of organ/tissue.

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9
Q

What are the different types of donor?

A 
Living donor (LRD, LNRD)
Deceased/Cadaveric
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10
Q

This donor is related to the recipient by blood within the fourth civil degree of consanguinity

A

Living related donor (LRD)

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11
Q

TRUE OR FALSE:

If the Px (recipient) suffers from hereditary disease, LRD is not recommended

A

TRUE

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12
Q

This donor not related to the recipient by blood or related by blood beyond the fourth civil degree of consanguinity but who is willing to donate

A

Living non-related donor (LNRD)

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13
Q

Related emotionally, commercial donor are considered as _________

A

LNRD

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14
Q

This donor individual who has just died and was previously known to be healthy patient who have suffered irreversible catastrophic brain injury of known etiology

A

Deceased/Cadaveric donor

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15
Q

If a Px had suffered from brain death/comatose, it has _____________________

A

irreversible neurological damage/cessation of entire brain = need ventilator/respirator to support breathing

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16
Q

A cadaveric/deceased donor must be free from _______________________

A

sepsis, transmissible disease, malignancy, primary brain tumor,

localized malignancy is acceptable

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17
Q

TRUE OR FALSE:

PMOD is possible as long as individual has met the criteria mentioned. It is only applicable to deceased/cadaveric donor

A

TRUE

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18
Q

PMOD stands for ______________

A

potential multiple organ donor

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19
Q

A donor is eligible if _______________________

A
  1. He/she must be 18 years old and above
  2. No existing clinical conditions
  3. The results of donor testing for relevant communicable disease agents are negative or nonreactive
  4. Free from risk factors for, and clinical evidence of, infection due to relevant communicable disease agents and diseases
  5. Free from communicable disease risks associated with xenotransplantation
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20
Q

What are the organ and tissues that ca be donated?

A 
ORGANS:
heart
lungs
liver
kidneys
intestine
pancreas
TISSUES:
cornea
tendons
valves
veins
skin
bones
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21
Q

What is the criteria used for suitability and matching. It is the national scoring system by which allocation of organ is based on (system for donor)

A

DASS or donor allocation scoring system

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22
Q

Which is amenable for transplantation?

A

ESOD or end stage organ disease

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23
Q

This is the system for organ

A

OSASS or Organ specific allocation scoring system

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24
Q

The individuals who are potential recipient. Diagnosed as end stage organ disease and medically suitable to receive organ graft

A

OTC (Organ transplant candidate)

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25
Q

KTC is ____________________

A

kidney transplant candidate (px w/ end stage renal disease) = qualified to receive kidney graft

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26
Q

LTC is ________________

A

liver transplant candidate (px w/ end stage liver disease) = Px w/ acute liver failure, specific metabolic disorder

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27
Q

This system contain national computerized data base ng lahat ng organ transplant candidate, transplant recipient (has already received organ graft), organ donors

A

PODRRS (Philippine Organ Donor and Recipient Registry System)

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28
Q

The Hospital transplant candidate waiting list contains __________________

A

database of all potential organ recipient of a particlaur transplant center

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29
Q

System for buong Pilipinas (Philippine data base of all potential organ recipient). Lahat ng transplant center of the Philippines.

A

National transplant candidate waiting list

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30
Q

Once removed from donors body, it must be transplanted within _______________

A 
Heart – can be transplanted 4-6hrs
Lungs – 4-6hrs
Liver – 8-12 hrs
Pancreas – 12-18hrs
Kidney – 1 – 1 ½ day (24-36hrs)
Intestines (Small) – 8-16 hrs
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31
Q

What is the scoring system/model to know sino iprioritize na Px for liver transplantation? It predict 90-day mortality while waiting for liver transplant

A

MELD (Model for end stage liver disease)

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32
Q

What are being considered or calculated in MELD?

A

Serum creatinine (set at 4mg/dL),
bilirubin,
INR (International normalized ratio – also used for coagulaition studies),
serum sodium (for px w/ dialysis 2x for the last week or 24hrs)

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33
Q

What is the criteria used for suitability and matching. It is the national scoring system by which allocation of organ is based on (system for donor)

A

DASS or donor allocation scoring system

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34
Q

Which is amenable for transplantation?

A

ESOD or end stage organ disease

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35
Q

This is the system for organ

A

OSASS or Organ specific allocation scoring system

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36
Q

The individuals who are potential recipient. Diagnosed as end stage organ disease and medically suitable to receive organ graft

A

OTC (Organ transplant candidate)

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37
Q

KTC is ____________________

A

kidney transplant candidate (px w/ end stage renal disease) = qualified to receive kidney graft

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38
Q

LTC is ________________

A

liver transplant candidate (px w/ end stage liver disease) = Px w/ acute liver failure, specific metabolic disorder

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39
Q

This system contain national computerized data base ng lahat ng organ transplant candidate, transplant recipient (has already received organ graft), organ donors

A

PODRRS (Philippine Organ Donor and Recipient Registry System)

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40
Q

The Hospital transplant candidate waiting list contains __________________

A

database of all potential organ recipient of a particlaur transplant center

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41
Q

System for buong Pilipinas (Philippine data base of all potential organ recipient). Lahat ng transplant center of the Philippines.

A

National transplant candidate waiting list

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42
Q

Once removed from donors body, it must be transplanted within _______________

A 
Heart – can be transplanted 4-6hrs
Lungs – 4-6hrs
Liver – 8-12 hrs
Pancreas – 12-18hrs
Kidney – 1 – 1 ½ day (24-36hrs)
Intestines (Small) – 8-16 hrs
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43
Q

What is the scoring system/model to know sino iprioritize na Px for liver transplantation? It predict 90-day mortality while waiting for liver transplant

A

MELD (Model for end stage liver disease)

44
Q

Which status represent Px w/ acute liver failure/dsase (estimated survival time: <7days) = highest priority?

A

Status 1

45
Q

What are being considered or calculated in PELD?

A 
growth failure (gender, height, weight), 
age at listing, 
bilirubin, 
INR, 
albumin
46
Q

What is the range of the score for MELD/PELD?

A

Score ranges 6 to 40 (equates the estimated 30-day survival rate from 90% to 7%) 6 = 90%, 4 = 7%

47
Q

What is the score to be considered as candidate for liver transplant?

A

> 17

48
Q

If the score is <15, Px is ________________

A

not considered as immediate candidate for transplantation. they are deferred for transplantation

49
Q

If the score is under 10, it must be _____________

A

recalculated annualy

50
Q

If the score is 11-18, it must be _____________

A

recalculate every 3mos

51
Q

If the score is 19-24, it must be _____________

A

recalculate once a month

52
Q

When is the final crossmatch performed prior to transplantation?

A

48hrs before

53
Q

What are the other factors for liver transplantation?

A 
supply, demand
location (gano kalapit) manggaling 
blood type
body sites (if too big/small)
pediatric = mas mahirap pag hanap ng donor
age
54
Q

What are the conditions for reconsideration to add exception points?

A

cholangiocarcinoma (bile duct cancer), cystic fibrosis, HAT/hepatic artery thrombosis, HCC/hepatocellular carcinoma, HPS/hepatopulmonary syndrome, metabolic syndrome/diseases

55
Q

What is the goal of pre-transplant infectious screening?

A 
identify condition na pwede madisqualify donor or recipient, 
treat active infection pre-transplant, 
define risk of infection/know strategies, 
prevent interventions (vaccine status).
56
Q

In donor screening, antibiotics must be administered at least _____________

A

14 days

57
Q

Which status represent that has a score of >29 = severely ill, potentially hospitalized

A

Status 2a

58
Q

Status 2b has a score of _____________

A

24-29 = end stage liver disease and severly ill but not requiring hospitalization (manage sa bahay)

59
Q

Status 3 has a score of ______________

A

<24 = Px w/ liver disease but too early to have cadaveric transplantation but suitable for live donor candidate

60
Q

What are the tests performed for transplant screening?

A

Blood type
HLA
Crossmatch
Serology

61
Q

if the blood type of a donor is O, allocate the organ to blood type ______

A

O

If none = allocate to other blood types ( PRIORITY SAME BLOOD TYPE)

Same with A, B, AB

62
Q

TRUE OR FALSE:

Rh type is a factor for donor matching

A

FALSE

It is NOT a factor

63
Q

This is checked for tissue type of all potential donors is considered in donor selection.

A

HLA

64
Q

When is the final crossmtach performed prior to transplantation?

A

48hrs before

65
Q

Serology tests are performed to _______________

A

detect potentially transmissible diseases

66
Q

TRUE OR FALSE:

Prevention strategies for infection also include educating the recipient and his or her family

A

TRUE

67
Q

What is the goal of pre-transplant infectious screening?

A

idenitify condition na pwede madisqualify donor or recipient, treat acitve infection pre-transplant, define risk of infection/know strategies, prevent interventions (vaccine status).

68
Q

In donor screening, antibiotics must be administered at least _____________

A

14 days

69
Q

TRUE OR FALSE:

Mycobacterium tuberculosis has been transmitted by transplantation

A

TRUE

70
Q

TRUE OR FALSE:

The most common bacterial infection that can be transmitted through organ transplantation is syphilis

A

FALSE

It is rarely transmitted but it is not a contraindication if the recipient is treated posttransplant with an appropriate course of benzathine penicillin

71
Q

What are the viral infections that is being screened for both donor and recipient?

A 
CMV
EBV
Other herpesviruses
Hepatitis B Virus
Hepatitis C Virus
HIV
West Nile Virus 
SARS
Rabies Virus
PTLT
HSV 
VZV
72
Q

Which viral infection can cause meningoencephalitis?

A

WNV

73
Q

TRUE OR FALSE:

Active systemic fungal infection in the donor is a contraindication to transplantation

A

TRUE

74
Q

The toxoplasmosis is a major concern in _____________

A

heart transplantation

Toxoplasma- seronegative recipient of a Toxoplasma-seropositive heart is at highest risk for developing active toxoplasmosis post-transplant

75
Q

Toxoplasmosis is rarely transmitted in __________

A

liver and kidney

76
Q

TRUE OR FALSE:

Screening donors for toxoplasmosis is routinely performed for every transplantation

A

FALSE

If non-cardiac transplantation, not routinely performed if non-cardiac donor

77
Q

In South and Latin America, what diseases is significant problem in endemic area?

A

Chagas Disease

78
Q

What is the republic act for authorizing the legacy or donation of all or part of a human body after death for specified purposes

A

RA 7170

79
Q

This is the Philippine HIV and AIDS policy act

A

RA 11166

80
Q

Who and when was the Organ Donation Act of 1991 approved?

A

January 7, 1992 by President Corazon C. Aquino

81
Q

According to Sec 6 of RA 7170, the persons who may become legatees or donees are: ______________________

A

hospital physician or surgeon, accredited medical/dental school, college, or university, organ bank storage facility and any specified individual

82
Q

What is the title of Sec 4 or RA 7170?

A

Person who may execute donation

83
Q

What is the title of Sec 6 or RA 7170?

A

Persons Who May Become Legatees or Donees

84
Q

What is the title of Sec 14 or RA 7170?

A

International Sharing of Human Organs or Tissues

85
Q

According to Sec 14 of RA 7170, the sharing of organs and tissues shall be made only through _________

A

exchange programs duly approved by DOH

86
Q

What is RA 8502?

A

Philippine AIDS Prevention and Control Act of 1998

87
Q

How many sections are there in RA 7170?

A

19 Sections

88
Q

How many sections and articles is the RA 8502?

A

9 articles with 52 sections

89
Q

When and who approved RA 8502?

A

February 13, 1998 by President Fidel V. Ramos

90
Q

This is the Philippine HIV and AIDS policy act

A

RA 11166

91
Q

The Philippine HIV and AIDS policy act consists of ___________

A

8 articles with 57 sections

92
Q

The Philippine HIV and AIDS policy act is approved by ___________

A

President Rodrigo R. Duterte in December 20, 2018

93
Q

This law is to modify certain provision of the original version to be more effective in dealing HIV condition in the Philippine setting

A

RA 11166 Philippine HIV and AIDS Policy Act

94
Q

The RA 11166 repeals for the purpose of ______________

A

RA 8504

95
Q

What are the guidelines on the donation of blood, tissue, or organ?

A

Tissue/organ is accepted if NEG for HIV
All donated bloos should be subjected to HIV testing
All POS donors for HIV shall be deferred, notified, counselled, referred for care and clinical management ASAP
POS donations is accepted for researchh purposes and subjected to strict sanitary disposal
Second testing may be demanded before transfusion/transplant except during emergency

96
Q

TRUE OR FALSE:

Individuals ages 15-18 yrs of age will no longer be required a consent from a parent or guardian for HIV testing but w/ consent to voluntarily be tested from child

A

TRUE

97
Q

TRUE OR FALSE:

Young person aged below 18 who is pregnant or engaged in high-risk behavior shall be eligible for HIV testing and counseling, with the assistance of a licensed social worker or health worker

A

FALSE

Below 16

98
Q

When will compulsory HIV testing be allowed?

A

test a person charged with any offenses punishable by law (rape, physical injury, simple seduction)
necessary to resolve relevant issues under EO 209 “family code of philippines”
prerequisite in blood donation

99
Q

What are the discriminatory acts and practices?

A

exclusion from credit and insurance services
discrimination in hospital and health institutions
denial of burial services
bullying in all forms (name calling, bullying in social media)

100
Q

Which is responsible for procuring of organs and for procedure of consent, donor management, and organ transportation that is accredited by PhilNOS?

A

Organ procurement organization (OPO)

101
Q

This refers to the designated trained health care professional who takes the central role and acts as liaison between the referring hospital and the retrieval and transplant team members

A

Transplant coordinator (TC)

102
Q

This refers to the TC who shall have the responsibility of coordinating the transplant candidate’s evaluation, management, and follow-up care

A

Clinical Transplant Coordinator

103
Q

Which TC is in-hospital services?

A

Clinical Transplant Coordinator

104
Q

This refers to a healthcare professional of organ procurement organization, designated to coordinate with the donor family and facility in order to facilitate a donation and proper transport of donated organ or tissue

A

Procurement Transplant Coordinator

105
Q

Which TC is responsible for coordinating outside the hospital?

A

Procurement Transplant Coordinator

106
Q

This rovides overall direction and system ng implementation of organ donation and transplantation sa buong pilipinas, through POTDTB under DOH

A

NODTP (National organ donation and transplantation program)

107
Q

The POTDTB (Philippine organ and tissue donation and transplantation board) observed as ________________

A

overseer in implementation and policies of organ donation and transplantation

Special Diagnostic Procedures (10 decks)

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