[ORAL EXAM] OTC Flashcards
An agent intended for use in diagnosis, mitigation, cure, treatment
or prophylaxis
Drug
taken by the body but has no approved
therapeutic use
Supplement
Intended to be applied to the external part of the body or mucous
membranes
Cosmetic
Refers to medicine which only be dispensed by a pharmacist to a
patient, upon presentation of a valid prescription
Prescription Drug
a written order and instruction for use
of speciNic drug for speciNic patient
Prescription
Refers to medicine which used for symptomatic relief of minor
ailments and which may be dispensed without a prescription
OTC Drug
What does RONPD stand for
Retail Outlet For Non-Prescription Drug
Refers to the scientiIically and internationally recognized name
of the active ingredients, as approved by the FDA
Generic Name
Which republic act approved by the FDA of the Generic Act
RA 6675
Intended to treat conditions that are chronic or long term
Maintenance Drug
Refers to the proprietary name given by the manufacturer to
distinguish its product from those of competitors
Brand Name
Intended for pain management – lose of perception of pain
Analgesic
Intended for reducing inNlammation in the body
Anti-InIlammatory
medical term for sensitivity to pain
Algesia
Two ways to measure body temperature
- Axillary most common
- Oral - most accurate
Intended for reducing fever
Antipyretic
A weak COX inhibitor (COX – Cyclooxygenase)
Paracetamol
Toxicity of Paracetamol
Hepatotoxicity
What does Hepatotoxicity stand for?
High accumulation of NAPQI (N-acetyl-p-benzoquinone imine)
Treatment for Hepatotoxicity
N-acetylcysteine
(just click)
Paracetamol is safe to use by special populations - – pregnant and lactating
moms, children
True or False:
Paracetamol has analgesic effect
True
True or False:
Paracetamol has antipyretic effect
True
Paracetamol is MOSTLY Antipyretic
True or False:
Paracetamol has anti-inflammatory effect
False
most populat Paracetamol brand
Biogesic
What are paracetamol drugs that contains caffeine that enhances analgesic effect
Saridon and Rexidol
the only chewable tablet of Paracetamol
Kiddilets
2 groups of Non-narcotics
- Paracetamol
- NSAID
Paracetamol daily intake mg/kg/day
125mg/kg/day
True or False
Are all maintenance drugs are OTC
False
some maintenance drugs are prescription drugs
2 groups of Analgesics:
- Narcotics
- Non Narcotics
What does COX stand for?
Cyclooxygenase
What does NSAID stand for?
Non-steroidal anti inflammatory drugs
what is responsible for inflammation
PGE 2 (Prostaglandins)
True or False
OTC NSAIDs are Non Selective
True
What is converted by COX to become Prostaglandins
Arachidonic Acid
What are NSAIDs inhibiting?
COX
to stop inflammation
(just click)
COX 1 - Constitutive Enzymes
> for homeostatic and maintenance function
COX 2 - Inducible Enzymes
> triggered and produced by particular stimulus
Which is bad COX 1 or COX 2?
COX 2
A prototype NSAID
Aspirin
Prototype NSAID - meaning dose dependent
give the ASPIRIN Dosage of each to function:
1. Analgesic
2. Anti-inflammatory
3. Antipyretic
4. Antiplatelet
Analgesic - less than 600mg/day
Anti-inflammatory - 3.2g - 4g/day
Antipyretic - 0.3g to 1.2g
Antiplatelet - no more than 325mg/day
the only OTC Aspirin
Asthromed
what is Aspirin Toxicity
Reye’s Syndrome
may cause Hepatic Failure
True or False
Mefenamic Acid is an antipyretic
False
True or False
Mefenamic Acid is an analgesic
False
Side effects of Aspirin
- Hyperuricemia
- Aspirin Toxicity (Reye’s Syndrome)
- GI Effects
- Low urine output
- NSAID-induced bronchial asthma
True or False
Aspirin can be given to children that are recovering from fever caused by viral infection
False
True or False
Ibuprofen is an antipyretic
True
True or False
Mefenamic Acid is an anti inflammatory
True
What is the only dosage strength of Mefenamic Acid in milligrams
250mg
What mefenamic acid brand names are OTC drugs
Dolfenal
Ponstan
What are the 2 Propionic Acid Derivatives
Ibuprofen
Naproxen
True or False
Ibuprofen is an analgesic
True