Oral Cavity Flashcards
What factors can cause cleft lip/palate?
maternal medication ingestion/exposure and maternal disease
A ________ cleft palate goes through the hard palate and soft palate
complete
The risk of having a 2nd child with cleft palate _______ if your first child has cleft palate
increases
Cleft palates are associated with syndromes at a rate of ______ percent, and is ______ percent for cleft lip.
50, 30
Stickler syndrome is due to a defect in _________ gene
COL (collagen)
_______ is a cleft lip/palate syndrome that is associated with eye abnormalities
Stickler syndrome
What syndrome is highly associated with lip pits?
Van der Woude, lip pits have 90% penetrance
Lip pits have a _____ percent penetrance in Van Der Woude syndrome.
90
Cardiac defects in 22q11 deletion syndrome are called _______.
conotruncal defects
How does Digeorge syndrome relate to the pharyngeal arches?
Individuals with diverge syndrome do not have a thymus (a derivative of the arches) and have abnormal parathyroid glands
_________ syndrome presents with swallowing difficulties due to low pharyngeal tone, learning disabilities, and cardiac defects
22q11.2 deletion syndrome
22q11.2 deletion syndrome is autosomal _______.
dominant
Goldenhar (Hemfacial microsomia) is an autosomal _______ disorder.
recessive
In Goldenhar syndrome craniofacial underdevelopment can occur due to abnormal development of what?
Arch 1 and arch 2 derivatives
What syndrome is associated with underdevelopment of the parotid gland and mandible, auricular abnormalities, and cervical vertebral anomalies?
Goldenhar/Hemifacial microsomia
Children with CHARGE syndrome commonly have a ______ antihelix fold.
linear
Pierre robin sequence leads to ________ hypoplasia.
mandibular