Oral Carcinomas

Question 1

Cancer def

Answer 1

– General term frequently used to indicate any of
various types of malignant neoplasms, most of
which invade surrounding tissues, may
metastasize to several sites, and are likely to recur
after attempted removal and to cause death to
the patient unless adequately treated

Question 2

Tumor def

Answer 2

swelling

Question 3

Harmatoma

Answer 3

disorganized overgrowth of normal tissue in its normal location

Question 4

choristoma def

Answer 4

growth of normal tissue in an abnormal location

Question 5

Neoplasm Def

Answer 5

Growth of abnormal tissue, may be either benign or malignant

Question 6

Adenoma

Answer 6

usually a benign neoplasm: Pleomorphic

adenoma, oncocytoma

Question 7

Carcinoma

Answer 7

– Malignant neoplasm derived from epithelial cells
• Surface (skin, mucosal): Basal cell carcinoma
• Glandular: Adenocarcinoma

Question 8

Sarcoma

Answer 8

Malignant neoplasm rom mesoderm

Question 9

Erythroplakia

Answer 9

• Red patch or plaque-like lesion that cannot be
clinically or pathologically diagnosed as any
other condition
• Often represents malignant change
– Up to 90% of erythroplakic lesions represent
severe epithelial dysplasia, carcinoma in situ, or
SCCa

Question 10

Erythroleukoplakia

Answer 10

– Frequently dysplasia or carcinoma in situ on

biopsy

Question 11

Proliferative Verrucous Leukoplakia

Answer 11

• High-risk form of leukoplakia
• Multiple keratotic plaques
– Roughened surface projections
• Persistent growth
– Exophytic, verrucous
• m:f 1:4 (female predilection)
• Minimal association with tobacco use
• Characterized by multiple, persistent, keratotic
plaques that over time progress to SCC
– Verrucous hyperplasia ®verrucous carcinoma ®
invasive squamous cell carcinoma
– Lesions rarely regress despite therapy