Optic nerve and visual pathways Flashcards

1
Q

==]]What do the outer segment of photoreceptors contain?

A

Discs containing light sensitive photopigment

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2
Q

What are the inner segment of photoreceptors made up of?

A

Cell body, axon and synaptic terminals

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3
Q

What is the main function of photoreceptors?

A

Phototransduction – absorb light, send electrical signal

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4
Q

Where are photopigments found?

A

Lie in discs of outer segments

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5
Q

What are photopigments in rods called?

A

Rhodopsin

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6
Q

What are photopigments in cones called?

A

Coneopsin

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7
Q

What are opsins?

A

Transmembrane proteins which contain the light sensitive molecule retinal

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8
Q

What do different opsin structures mean?

A

Mean retinal absorbs different wavelengths of light

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9
Q

What causes phototransduction?

A

Effect of a photon on a rhodopsin molecule

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10
Q

What happens during phototransduction?

A

Effect of a photon on a rhodopsin molecule
Triggers conformation change to all-trans form
This change triggers changes in the opsin structure
This in turn triggers a cascade within the cell

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11
Q

What is the pathway of signals in the retina?

A

Photoreceptor → bipolar cell → retinal ganglion cell

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12
Q

What cells modulate signals in the retina?

A

Horizontal and apocrine cells

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13
Q

What artery supplies the outer 1/3 of the retina?

A

Choroid (posterior ciliary arteries)

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14
Q

What artery supplies the inner 1/3 of the retina?

A

Central retinal artery

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15
Q

Which gland is responsible for baseline tear formation?

A

Accessory lacrimal gland

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16
Q

Which is the outermost layer of the tear film?

A

Lipid

17
Q

What is the purpose of lipid layer in the tear film?

A

Prevents evaporation

18
Q

Which gland produces the lipids in the tear film?

A

Meibomian, Zeis, Moll

19
Q

What is the innermost layer of the tear film?

A

Mucus

20
Q

Which gland produces the mucus layer in the tear film?

A

Conjunctival goblet cell

21
Q

Which layers are most commonly implicated in dry eye?

A

Lipid and aqueous