optho Flashcards
Features of horners syndrome
Miosis
Ptosis
Enopthalmos - sunken in
Anihidrosis
Causes of optic neuritis
MS
Diabetes
Syphilis
Management of optic neuritis
High dose steroids
(Recovery 4-6 weeks)
Features of optic neuritis
Unilateral decrease in visual acuity - over hours or days
Poor discrimination of colours
Pain worse on eye movement
Relative afferent pupillary defect
Central scotoma
Investigation of optic neuritis
MRI of brain with orbits with contrast
Is diagnostic
A 50-year-old woman presents to the emergency department with severe left eye pain over the last 4 hours. She has no changes in her vision, nausea, or vomiting and has a past medical history of rheumatoid arthritis and takes methotrexate. She does not wear any contact lenses.
Her pulse is 92 bpm, her blood pressure is 123/75 mmHg, and she is afebrile. The left eye is deep red and injected throughout. When palpating the eye, the injected vessels do not move and her eye is tender. The right eye is normal and visual fields and acuity are intact.
What is the most likely diagnosis?
Scleritis
Main features = extremely painful, deep red injected eye, patient has systemic connective tissue disease, reduced visual acuity, blurred vision
Management of scleritis
same day assessment by an ophthalmologist
Oral NSAIDS = 1st
Oral glucocorticoids - more severe
Immunosuppressive drugs for resistant cases
What is orbital cellulitis
result of an infection affecting the fat and muscles posterior to the orbital septum - not involving the globe
Usually caused by URTI spreading from sinuses
Is a medical emergency - risk of cavernous sinus thrombosis and intracranial spread
Risk factors of orbital cellulitis
Childhood 7-12 years
Previous sinus infection
No Hib vaccine
Recent eyelid infection
Ear or facial infection
Presentation of orbital cellulitis
Redness and swelling around the eye
Severe ocular pain
Visual disturbance
Proptosis
Opthalmoplegia
Eyelid oedema and ptosis
Drowsiness +/- nausea and vomiting in meningeal involvement
IVX orbital cellulitis
FBC
Clinical examination
CT with contrast
Blood cultures and microbial swab
MXM orbital cellulitis
Hospital admission for IV abx
Leading mechanisms for ocular trauma
Blunt trauma
Penetrating injury
What type of fracture associated with blunt force
Blow out fracture ie fist to the face/squash ball
Structures involved in blow out fracture
herniation of the fat
Tethering of inferior recuts
Infraorbital nerve
Inferior nerve get trapped in inferior wall of orbit
What is hyphaema
Blood in anterior chamber
What medical condition could show a dislocated lense
Marfans
SEIDELS
fluoroscein drops into the eye - would show any aqueous damage
Sympathetic opthalmia
Exposure to intraocular antigens > due to penetrating injury to one eye > but can get auto-immune reaction in both eyes
Inflammation in both eyes > may lead to penetrating blindness
How to remove small foreign body on cornea
slit lamp
Local anaesthetic
Edge of needle > scrape of scoop
Cover with chloramphenicol ointment after
Investigation for intro-ocular foreign body
imaging - x-ray or CT
Chemical injury management
Quick history
Check toxbase if possible
Check pH
Irrigate +++ (2L saline)
Then assess under slit lamp
Ametropia
refractive error present - light focused in front of or behind retina
There are 3 refractive states:
Myopia - before the retina
Emmetropia
Hyperopia - after retina
Emmetropia
Normal vision
Anisometropia
Significant difference between right and left ametropia
Anisometropia
Significant difference between right and left ametropia
Amblyopia
Lazy eye
Astigmatism
Rugby ball eye shape - blurry vision
Spectacle prescriptions
+3.00 / -2.00 x 90
Recommended imaging for optic neuritis
MRI brain and orbits with contrast
Steadily worsening loss of vision over the previous few months - followed by a sudden deterioration
Examination findings of a central scotoma and red patches
Wet age-related macular degeneration
Dendritic corneal ulcer
Herpes simplex virus
Tx. - topical acyclovir
MoA of timolol
Used in primary open-angle glaucoma by reducing aqueous production
MoA of prostaglandin analogues
Increases uveoscleral outflow
MoA sympathomimetics
Reduces aqueous production and increases outflow
Carbonic anhydrase inhibitors
Reduces aqueous production
MoA miotics
Increases uveoscleral outflow
Ptosis + dilated pupil
3rd nerve palsy
Ptosis + constricted pupil
Horners
What usually causes blow out fractures
Direct blow to the central orbit from a fist or a ball
Most common blowout fracture
Inferior blowout - orbital fat prolapses into the maxillary sinus and may be joined by prolapse of the inferior recuts muscle resulting in Diplopia
Organs with autonomic innervation
Sympathetic innervation of arterioles, sweat glands and arrector muscles
Smooth muscles of iris and ciliary body associated with the lens
Lacrimal glands
Salivary glands
Sympathetic innervation route -
originates from autonomic centres
Passes down spinal cord
Exits spinal cord with T1 - L2 spinal nerves
Travel to sympathetic chains running the length of vertebral column
Pass into all spinal nerves
Pass into splanchnic nerves > organs
What is the commonest cause of a red eye
conjunctivitis 30% of all primary care cases
Red painful eye and photophobia , fluorescein and slit lamp exam - dendritic ulcer
What is the causative organism
HSV
20 year old female presents with red, severely painful eyes - phenylephrine drops > redness does not blanch
What is the mxm for this
Oral NSAIDs
For scleritis
What is used to test between episcleritis and scleritis
phenylephrine drops - non-blanching is scleritis
Which conditions can cause anterior uveitis
UC
Syphilis
Leukaemia
HLA B27
Child has a 1 day history of redness and swelling around the eyes with pain on eye movement and history of a URTI - what is the initial investigation
CT scan
65yr old woman complains of sudden, painless loss of vision since this morning - L fundus shows flame haemorrhage and RAPD
What is the diagnosis
Central Vein occlusion
67 year old man with T2D, present with visual disturbances for 3 hours - reports black spots obscuring left eye with a red hue
Vitreous haemorrhage
What is a risk factor for retinal detachment
Myopia
What is seen on fundoscopy of someone with a retinal artery occlusion
Pale retina with a cherry red spot
Retinitis pigmentosa
bony spicule
What is the main cause of a retinal artery occlusion
Giant cell arteritis
3 year old is brought to GP as his mother is concerned about cross-eyes - corneal light reflection tests confirms strabismus .
What is the management ?
Opthalmology clinic where they are given an eye patch
Eye changes classically seen in thyroid eye disease / Graves’ disease
inability to close the eyelids
Eye is down and out
3rd nerve palsy
What in thyroid eye disease would warrant an urgent review by opthalmology
Optic disc swelling
A 60 year old diabetic patient has microaneurysms and new blood vessel formation - no changes on the macula
Definitive management ?
Pan-retinal laser coagulopathy
What is a risk factor for developing glaucoma
Steroids
Most common cause for retinal artery occlusion
Arteroi-sclerosis related thrombosis
Most common cause for retinal artery occlusion
Arteroi-sclerosis related thrombosis
What describes the change in the optic disc seen in glaucoma
Increased cup to disc ration - cupping
What isn’t a feature of angle-closure glaucoma
Symptoms worse on bright light - patients actually find it worse in dark room due to dilation > putting pressuring on trabecular mesh work or something
Which type of visual field loss is associated with open angle glaucoma
nasal stepping - peripheral vision is lost first in open angle glaucoma
Central scotoma
macular degeneration
What are the side effects of 1st line for open angle glaucoma
Change in eye colour / pigment
Longer eyelashes
Latintaprost
What do you see with a right sided trochlear nerve palsy
up and outwards
Trochlear nerve > SO > attaches behind to move it forwards and down so if not working it will start to drift up
Oculomotor nerve palsy
CN III - down and out
Ptosis, diplopia and eye that is fixed down and laterally - an aneurysm of which vessel is most commonly implicated
Left posterior communicating artery
Which foramen does CN III IV and VI pass through
Superior orbital fissure
On visualising the retina of an 88-year old man with increasingly blurred vision and reduced central vision, choroidal neovascularisation
Diagnosis ?
Wet macular degeneration
Tx for dry macular degeneration
Vit C, E, beta carotene and zinc
Senior woman diagnosed with dry macular degeneration - what is seen on fundoscopy
drusen
What is not associated with cataract development
Hypertension
What is the most associated risk factors for cataracts
Old age
Steroids
DM
Smoking
What is a sign of cataract
A defect in the red reflex
75 year old present with left homonymous hemianopia - where is the lesion
Right optic tract
55 year old male present with bitemporal hemianopia - has a PMH of pituitary adenoma - where is the lesion
Optic chiasm - tunica celiac
Patient presents to A&E after a RTA - left homonymous hemianopia with macular sparing - where is the lesion
Occipital cortex - due to macular sparing (further back in the brain)
III nerve palsy
Least common in optho
Innervates everything else
IV nerve palsy
Superior oblique - to look left and down (R)
And so eye is looking up - patient has vertical double vision
Depression in adduction
VI Nerve Palsy
Most common
Most serious
Lateral recuts is not working and so cannot abduct and also turns inward
Causes:
Micro vascular
Raised intracranial pressure
Tumours + congenital