opthalmology Flashcards
where is aqueous humour produced?
ciliary body
what is the purpose of aqueous humour?
supply nutrients to the cornea and lens
explain the course of aqueous humour
travels from the posterior chamber through the pupil into the anterior chamber then drains out of the anterior chamber through 2 independent pathways
what are the 2 pathways that aqueous humour drains out of the anterior chamber?
trabecular meshwork into canal of Schlemm
uveoscleral pathway
what causes primary open angle glaucoma?
resistance to outflow of aqueous humour through trabecular meshwork, causing IOP to rise
give 5 risk factors for open angle glaucoma
myopia (short sighted)
elderly
ocular hypertension
T2DM
cardiovascular disease
how does open angle glaucoma present?
slow and chronic course
usually affecting both eyes
what is the pattern of vision loss in open angle glaucoma?
initially loss of peripheral vision usually in superior visual field before inferior visual field
what are the clinical findings of open angle glaucoma?
increased IOP
visual field defects
cupped discs on fundoscopy
what is the gold standard investigation to measure IOP?
goldmann applanation tonometer
when is treatment for open angle glaucoma started?
when IOP is >24mmHg
what are the 3 management options for open angle glaucoma?
laser management
medical management
surgical management
what is the first line medical management for open angle glaucoma?
prostaglandin analogues e.g. latanoprost
what are the 2 side effects of prostaglandin analogues used in the treatment of open angle glaucoma?
eyelash growth
eyelid and iris pigmentation
aside from prostaglandin analogues, what other medications are used in the treatment of open angle glaucoma?
beta blockers (timolol)
parasympathetics (pilocarpine)
carbonic anhydrase inhibitors (acetazolamide)