GI inc liver Flashcards
what is acute cholangitis?
infection of the biliary tree caused by biliary outflow obstruction
how does acute cholangitis present?
RUQ pain
fever
jaundice
what is biliary colic?
RUQ pain caused by impacted gallstone at the neck of the gallbladder
what is the trigger for biliary colic?
consumption of fatty foods
how does biliary colic present?
RUQ pain
no fever no jaundice
how does cholecystitis present?
RUQ pain
fever
no jaundice
what is the pathophysiology of acute pancreatitis?
inflammation caused by hypersecretion or back flow of exocrine enzymes which result in auto digestion of the pancreas
what are the causes of pancreatitis?
I - idiopathic
G - gallstones
E - ethanol
T - trauma
S - steroids
M - malignancy / mumps
A - autoimmumne disease
S - scorpion sting
H - hypercalcaemia
E - ERCP
D - drugs
how does acute pancreatitis present?
epigastric pain that radiates to back, is worse after meals and is better leaning forward
nausea and vomiting
decreased appetite
what is the diagnostic criteria for acute pancreatitis?
2 of 3 of:
abdo pain and history suggestive of acute pancreatitis
serum amylase / lipase over 3x the upper lim of normal
imaging findings suggestive
what are the 2 most common causes of acute pancreatitis?
gallstones and alcohol
what is the management of gallstone pancreatitis?
ERCP
cholecystectomy on all pts in the same hospital admission
what is the management of alcohol induced pancreatitis?
benzos for withdrawal
thiamine, folate and B12
how does the pain in appendicitis migrate?
initially it produces umbilical pain
as it progresses it produces localised pain in the right iliac fossa
what is Murphys triad in appendicitis?
low grade fever
nausea and vomiting
right iliac fossa pain
what is the first line imaging in appendicitis?
ultrasound
what is the management of appendicitis?
appendectomy
what is cholecystitis?
inflammation of the gallbladder usually secondary to gallstones
what is the most common type of colorectal cancer?
adenocarcinoma
what do most colorectal cancers arise from?
pre cancerous polyps
what is reccomended for pts who have red flag symptoms for colorectal cancer?
faecal immunoglobulin testing (FIT)
what happens if the FIT is positive?
the pt should be referred on an urgent suspected cancer pathway (2 wk wait)
what is the gold standard diagnostic test for colorectal cancer?
colonoscopy
almost all coeliac pts are positive for what?
HLA DQ2