Opthalmology Flashcards
glaucoma
optic neuropathy secondary to increased ocular pressure >21mmHg
patho of primary open angle glaucoma
- Trabuecular network has increases resistance = high IOP = death to retinal ganglion
Ix Primary open angle glaucoma
- slit lamp = cupping
- Goldmann applanation tonometry
- gonioscopy = visualise angle between iris and cornea
- visual field assessment
Open Angle glaucoma tx
- latanoprost drops (prostaglandin analogue)= increases uveoscleral outflow )negative = increased eyelash length)
- BB timolol = reduces aqueous production
- Surgery = trabeculectomy
- 360 Laser = trabeculoplasty = NICE guidance
acute Closed Angle Glaucoma patho
- iris bulges covering trabecular meshwork = acute narrowing of anterior chamber and sudden rise in IOP as preventing drainage
- sight threatening = emergency
RF open angle glaucoma
- Age
- FHx
- Black ethnic origin
- Myopia (nearsightedness)
S+S acute angle closure glaucoma
- severely painful red eye
- blurred vision
- halos around lights
- headache, N+V
- red eye, hazy cornea
- decreased acuity
- mid dilated pupil, fixed size pupil
- Hard eyeball
Meds that can precipitate acute closed angle glaucoma
- adrenergics = noradrenaline
- Anticholinergics = oxybutynin
- TCA = amitriptyline
tx Acute Closed Angle Glaucoma
- initial = lie down
- IV acetazolamide= reduce aqueous production
- pilocarpine drops = constricts pupil
- iodipine drops
- bilateral peripheral laser iridotomy = definitive
presentation closed angle glaucoma
- fluctuant pain
- headaches
- blurred vision
- halos around lights
Cataracts patho
opacification of lens
- nuclear = old age = middle
- cortical = wedge shaped spokes
- posterior subcapsular = steroids use
RF cataracts
- aging
- smoking
= alcohol - dm
- steroids
- myotonic dystrophy
- hypercalcaemia
dx cataracts
slit lamp
presentation cataracts
- asymmetrical
- slow reduction acuity
- progressive blurring
- colours more faded
- starbursts around lights
- loss of red reflex
tx cataracts
- surgery = phacoemulsification
risks cataracts surgery
- posterior capsule opacification
- endophthalmitis
- posterior capsule rupture
- retinal detachment
diabetic retinopathy patho
- hyper causes damage to endothelium/pericytes
- changes vascular permeability
- exudates and microaneurysms
- retinal ischaemia = VEGF = new leaky vessels (neovascularization)
Ix diabetic retinopathy
- slit lamo
- retinal photography
sudden complete loss of vision in diabetes
vitreous haemorrhage
- Minor = floaters
- Severe = painless loss vision
- will see red opacity obscuring retina
- Mx = vitrectomy
moderate NPDR in DNTx DN
- control BP and DM
- anti VEGF injections
- photocoagulation
hypertensive retinopathy staging
1 =mild generalized retinal arteriolar narrowing
2 = definite focal narrowing and av nipping
3 = 1 plus haemorrhages, exudates and cotton wool spots
4 = 3 plus papilloedema
rf age related macular degeneration
- age
- cvd
4 layers of macula
- Choroid layer
- Bruchs membrane
- Retinal pigment epithelium
- Photoreceptors
S+S MD
- gradual loss central vision
- reduced acuity
- metamorphosia = wavy straight lines
- struggle to read small text
- drusen = yellow deposits of proteins and lipids between RPE and bruch
- atrophy of rpe
- degeneration of photoreceptors
- scotoma
Ix MD
- fluorescien angiography
- photography
- Optical coherence tomography
- slit lamp
Mx dry MD
- conservative
drusen = dry
Is wet MD neovascular or not
- Neovascular
- new vessels develop from choroid layer and grow into retina = leak and cause oedema
MD wet treatment
- anti VEGF, steroids
- wet = neovascularisation
retinal detatchment S+S
- flashes and floaters
- decreased acuity and peripheral vision
- curtain
- distorted images
= emergency - most common = rhegmatogenous
patho RD
- holes and tears in neurosensory layer retina
- fluid separates sensory retina from RPE
Mx RD
- tilt head
- laser photocoagulation
- surgery = vitrectomy and gas/oil tamponade/scleral buckle with cryotherapy to secure
retinitis pigmentosa
- genetic
- progressive retinal degeneration
- tunnel vision and reduced visual acuity
- fundoscopy = peripheral bone spicule pigmentation, optic disc pallor, vessel attenutation
S+S conjunctivitis
- itchy
- sticky
- uncomfortable red
- weepy
conjunctivitis causes
- bacterial = staph, gonococcus (sexual transmission) = purulent discharge, more likely unilateral
- viral = adenovirus = serous discharge, more likely bilateral
mx conj
- bacterial = chloramphenicol
dry eyes
- gritty eyes
- idiopathic, RA, sjogrens
- Dx = schirmer test, antibody tests, fluouroscein drops and blue light
- mx = artificial tears, topical cyclosporin, punctal plugs
episcleritis is
benign and self limiting inflammation of episclera
S+S episcleritis
- red eye (localised or diffused)
- watering
- not painful
- mild photophobia
- engorged vessels
episcleritis patho and mx
inflammation of episclera = between sclera and conj
- NSAIDs
differentiation in scleritis
- cotton wool application with phenylephrine drops
- epi = vessels blanch
scleritis S+S
- severe eye pain
- dull boring pain
- red eye
- POM
- photophobia
- fall in acuity
- blue sclera (thin sclera)
scleritis general
inflammation of sclera
- may lead to perforation
- RA and granulomatosis common in
- phenylephrine application
- urgent referral, oral steroids, immunosuppression
Mx scleritis
- urgent refer
- NSAIDs
- steroids
- Immunosuppress
anterior uveitis patho
- inflammation in anterior chamber of eye
- AC infiltrated by neutrophils lymph and macro
- hypopyon = fluid collection containing inflammatory cells
RF anterior uveitis
- seronegative spond
- IBD
- sarcoidosis
- Behcets
S+S anterior uveitis
- red eye
- blurred vision
- painful
- pus
- lacrimation
- miosis
- ciliary flush
5 clinical signs - red eye
- hypopyon = pus
- flare (protein)
- posterior synechiae = abnormal pupil
- keratic precipitates
AU ix and mx
- slit lamp = red eye
- urgent referral
-steroids (normally topical) - pupil dialtion with cycloplegics (atropine)
GCA S+S
- headache
- raised inflammatory markers
- pale disc
= anterior ischaemic optic neuropathy = arteritic (GCA) or non arteritic = insufficient blood supply, painless
optic neuritis
- inflammation optic nerve
- MS = will respond to steroids
- painful eye movements, decreased acuity, less red colours
- RAPD
- Ix = MRI
- Mx steroids
RAPD
- swinging light test
- normal eye = constricts
- both eyes dilate = abnormal
central retinal artery occlusion
- Sudden painless loss in vision
- RAPD
- Pale retina with cherry red spot
- stroke
- carotid artery atherosclerosis = most common cause = CA doppler
central retinal vein occlusion
- sudden painless loss of vision
- stormy sunset appearance
orbital cellulitis S+S
- severe ocular pain
- POM
- diplopia
- visual disturbance
- CT orbit = gold standard
- IV Abx and surgical drainage
(periorbital = no pain)
S+S trauma (small objects)
- severe eye pain
- hyphema = blood
- red eye
- iris prolapse
- urgent referral
- XR or CT = NO MRI
- numbing drops to examine = tetracaine
S+S opthalmic shingles
- vesicular rash around eye
- neuralgia
- rash on top of nose = hutchinsons sign
Ix and mx op shing
- clinical
- fluroescein dye and UV light = dendritic ulcer
- aciclovir
blepharitis
- inflammation
- gritty sticky and red
- seborrheic dermatitis
- hot compress
- tears
chalazion
- retention of cyst of meibomian gland
- firm and painlesss
stye
- infection of glands
- hot compress
- abx drops if bacterial
down and out
3rd nerve palsy
4th enrve palsy
- ## stiff neck
pointing in
6th nerve palsy
horners syndrome
- ptosis
- miosis
- anhidrosis
sympathetic lesion - preganglionic = pancoast tumour
- post ganglionic = carotid dissection = painful
fundoscopy findings diabetic retinopathy
- cotton wool spots
- microaneurysms
- hard exudates
- blot haemorrhages
- neovascularisation
grading diabetic retinopathy
- background = aneurysms, retinal haem, hard exudates, cotton wool
- pre-proliferative = beading, multiple blot haem, IMRA
- proliferative = neovascularisation and vitreous haem
complications diabetic retinopathy
- vision loss
- retinal detatchment
- vitreous haem
- optic neuropathy
- cataracts
Mx diabetic neuropathy
- non proliferative = monitor
proliferative - PRP
- Anti VEGF
- Surgery
herpetic keratitis S+S, Mx
- primary = mild inflammation
recurrent - painful red eye
- photophobia
- vessicles
- watery dc and reduced acuity
- fluorescein stain = dendritic corneal ulcer
- mx = antivirals
hypertensive retinopathy findings
- cotton wool
- silver wiring
- hard exudates
- arteriovenous nipping
- papilloedema
- retinal haemorrhages
keith wagener classification HTN ret
1 = mild narrowing arterioles
2 = focal constriction of blood vessels and av nicking
3 = cotton wool exudates and haem
4 = papilloedema
Bacterial keratitis
- emergency
- bacterial infection cornea
- contact lens use
- corneal scrape
- topical quinolone
pseudomonas aerginosa most common