Cardio Flashcards
what is heart rate
HR = CO X SV
What is the parasympathetic input to the heart and describe the mechanism
- Vagus nerve
- When stimulated ACH binds to M2 receptors –> decrease HR
What is the sympathetic input to the heart and describe the mechanism
- Postganglionic fibres from cardiac plexuses
- release noradrenaline which acts on B1 adrenoreceptors
- Increases HR and force of contraction
How to increase BP
- Baroreceptors detect decrease
- Synpathetic activated
- Cardiac accelerator centre in MO
- HR increased, contraction increased, vasocontriction
How to decrease BP
- Baroreceptors detect
- Parasympathetic activated
- GN and V nerves carry to MO = cardiac decelerator centre
- HR reduced, vasodilation
What is cardiac output
CO = SV X HR
What is stroke volume
Difference between EDV and ESV
What is CVP
pressure in vena cava as it enters RA
What is TPR
pressure in arteries blood must overcome as it passes through them = afterload
Starlings law
the more the heart chambers fill the stronger the ventricular contraction therefore the greater the stroke volume
Mean arterial blood pressure
MAP = CO X TPR
Virchows triad
- Stasis of blood flow
- Hypercoagulability
- Vessel wall injury
Where does the RCA supply?
- Right atrium
- Right ventricle
- Inferior aspect of left ventricle
- Posterior septal area
Where does circumflex artery supply
- Left atrium
- Posterior aspect of left ventricle
Where does LAD supply
- Anterior aspect of left ventricle
- Anterior aspect of septum
S+S of MI
- Central crushing chest pain
- Pain to jaws or amrs
- N+V
- Sweating
- Doom
- SOB and palpitations
STEMI ECG changes
- ST segment elevation
- New LBBB
NSTEMI ECG changes
- ST depression
- T wave inversion
Ix for MI
- ECG
- Troponin
- Baseline bloods
Initial Mx for MI/ACS
MONA/PAIN
- Perform ECG
- Morphine
- Oxygen if sats <94
- Nitrate
- Aspirin 300mg
What to do if suspect ACS in last 72 hrs?
- Refer to hospital for same day assessment
Mx STEMI
- Within 120 minutes = PCI. Prasugrel (clopi of on ac) and aspirin
- > 120 minutes = thrombolysis
Secondary prevention STEMI
ACAB
- Acei
- Clopidogrel
- Aspirin and statin
- BB
NSTEMI mx
BATMAN
- Base decision about angio and PCI on GRACE score
- Aspirin 300mg stat
- Ticagrelor 180mg stat dose
- Morphine
- Antithrombin therapy = fondaparinux
- Nitrate