Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immunology > Opportunistic mycoses > Flashcards

Opportunistic mycoses Flashcards

1
Q

two way an opportunistic fungus will get into the body

A

compromised anatomic and physical barriers
~ airborne like aspergillus settles on wound
othres from soil
–others from catheter tubes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Two people susceptible to fungal infections

A

cancer patients of lyphohematolotigs and people with inherited inmmunodeficiencies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

chemo and radiation are good places for fungal infections, t/f

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what two diseases are most common cause of fungal infection in hematopoetic stem cell or transplant patients

A

candida or aspergillus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

This latent disease can increase host suspetibility to other infectsion

A

CMV and Epstein barr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Because hiv targets CD4+, this results in

A

oppotunity for fungi contolled by CDT4 helpesr to flourish

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Candida are complex and do

A

phenotype switching

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

This form of candida is seen in all humans

A

yeast and hypha morphotyes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

while yeast and hyphea are more often seen, this form of candidia can also be seen in host

A

pseudohyphae or chains of yeast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

C. albicans are or are not capsulated

A

they are non-capsulated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is the invasive form of C. albicans

A

pseudohyphal form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

where do candida live

A

commensal part of human floura and like the GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

most cases of candidiases come from

A

person’s own organism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

3 out of 4 women experience

A

vulvovaginalis candidiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the most common microbial infection in AIDS

A

candidiasis, lots of THRUSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the three major types of virulence determinants

A

adhesions, phenotype switching and enZ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

C. albicans produces these so they can bind to various parts of the host body

A

adhesions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

the hallmark of invasive C. albicans is this form

A

invasive pseudohyphae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

C. Albicans secrete these and it destructs host tissues

A

enZ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

stents, caths, shunts, ect are all example of

A

biofilms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

C.Albicans can stick to biofilms, this is dangerous bec

A

they evade immunse sytem and can cause failure of biofilm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Infection sights of C. albicans

A

skin and mucosal, or moist skin
people on antibiotics
people with dermatisis
site of surgiers like arterial, venous, central venous and urinary catheters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Central venous catheters

Broad=spectrum antibiotics and surgery with gut transection result in

A

higher suspectiblity to caindidiasis infection in adults and neonates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Candidi pseudo hypahe have or don’t have septa

A

NO septa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What does aspergillus have

A

hyphae SEPTA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What type of drug resistances makes non-albinas hard to treate

A

azole resistance

27
Q

Why is oral candidiasis difficult to threat in asthmatics

A

bc get from steroids in inhalers and they need inhaler

28
Q

Cryptococcus causes

A

cryptococcosis

29
Q

What do they look like: Cryptococcus

A

uninucleate budding yeast with a polyscach capsule

30
Q

where are cryptococcus distributed?

A

worldwide and all over soil

guano from birds

31
Q

Are cryptococcus a normal part of human floura

A

NO

32
Q

Which strain of Cryptococcus has an outbreak recoding

A

C. gatti

33
Q

Is Cryptococcosis a global disease?

A

yes; seen in pacific northwest and sub-sahra Africa

34
Q

What strains of cryptococcosis is the virulent strain

A

CAPUSLATED… acapsulated are avirulent

35
Q

how do we prognosis w/ cryptococcosis

A

see capsuleted presnence in serum of CCF and blood

36
Q

Whats the deal with cryptocococcis capsule

A

it’s Antiphagocytic-capsule conceals the fungal wll ligands that our body like phagocytes would regonize and it makes them too big for ingestoin

37
Q

What is the location of cryptococossis inside a human host

A

extracellular

we inhale airborne yeast

38
Q

After we inhale airborn cryptococcossis, what happens in our bodies

A

they rehydrate and get their capsule back

39
Q

Meningitis is the first indicaiton of which type of infection

A

crytpococcal infection

40
Q

what is the most serious manifestation of cryptococcosus

A

meningitis

41
Q

Aspergillus is a mold with

A

septate hyphae (crosswall mycelia) + conidia

42
Q

does asperillus have a yeast form

A

no

43
Q

Epi of aspergillus

A

worldwide, in house dust, vegitation, and airborne

44
Q

Construciton project have been associated with outbreaks in

A

aspergillus

45
Q

How does aspergillus destroy host tissue

A

hydrolytic enZ and toxin production to evade macrophages

46
Q

This population of individuals have increased suspetiblity to aspergillus

A

CMI or compromised adaptive immunity

47
Q

CMI more likely to get Aspergillus, how come

A

suprresed innate host defense

48
Q

Neutropenic patients are at risk for

A

aspergillus infection

49
Q

leads to localized inflammation
necrotizing in lung
can invade blood vessels leading to brain/liver/ect

A

invasive asperogillosis

50
Q

What is the big challenge to scientists when diagnosis aspergillus

A

making a quick diagnosis

51
Q

Rhizopus, mucor and fusarium are

A

Zygomycosis: emerging opportunistic fungal pathogens

52
Q

Zygomycosis include disease processes caused by members of:

A

Zygomycetes

53
Q

Zygomycetes (especially Rhizopus, Mucor, Fusarium) have emerged as

A

cause of morbidity, mortality in immunocompromised patients

54
Q

Morphology of Zygomycetes in envi

A

mold in envi and host

55
Q

In tissue, the hyphae of rhizopus ad mucro are: septate or aseptate

A

aseptate, no cross walls

56
Q

Fusarium are septate or aseptate hyphae

A

Septate!!! like aspergillus

57
Q

where are zygomycosis found

A

in soil, envir, plants, fruit, moldy bread

58
Q

Epidemiology of Zygomycosis; rhizopus, mucor, fusarium

A

worldwide and can be found in air vents

59
Q

Are there virulence determinants for zygomycosis

A

no

60
Q

how do we aquire zygomycosis

A

inhaltion, ingestion, contamination by spores

61
Q

Acidodic patients with diabets are suspetible to

A

rhizopus bc of their ketone reductase

62
Q

this has been seen as a breaksthrough infection in bone marrow transplant patients get antifungal prophylaxis with azoles

A

Zygomycosese bc the azoles dont work on them

63
Q

Zygomycosses mimick

A

common bactetial infections an other mycosis

Immunology (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions