Opium/opiate Misuse Flashcards

1
Q

how is heroine produced

A

acetylation of morphine

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2
Q

until when was heroine freely available

A

19th C

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3
Q

which act, in which year, prevented import of opium except for medical purposes in the USA

A

harrison act 1914

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4
Q

what decade was the manufacture and medical use of heroine banned in

A

1920s

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5
Q

what are the effects of taking opiates

A

nausea and itching followed by warm feeling, sedation, drowsiness, feelings of competence, optimism, power and detachment

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6
Q

which classes of receptor are stimulated by opiates

A

mu, kappa, delta

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7
Q

what rae the effects of opiate binding to u receptors

A

analgesia, euphoria, respiratory repression, inhibition of gastrointestinal smooth muscles and miosis

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8
Q

what are the effects of opiate binding to k receptors

A

analgesia, sedation, hallucinations, hypothermia

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9
Q

what are the effects of opiate binding to delta receptors

A

analgesia, respiratory depression, inhibition of gastrointestinal smooth muscle

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10
Q

how is repiratory depression potentiated

A

alcohol

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11
Q

what were opiates used to treat in greek/roman times

A

insomnia,pain, cough, vomiting and diarhhoea

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