History of Toxicology Flashcards
in what year was the “Treatise on Poisons” by mathieu Orfila published
1817
who published the first treatise on industial hygiene in 1831
Charles Turner Thackrah
in which decade was morphine first isolated from opium and quinine isolated from cinchana bark
1830’s
which two scientists developed the first reliable tests for arsenic around 1836/1842
marsh and reinsch
what did yamagiwa and ichikawa prove in 1915
coal tar leads to tumors- first demonstration of chemical carcinogens
what toxin did the team lead by Gerhard Schroder develop
organophosphate insectisides and nerve gases such as sarin and tabun
what is the anti-lewisite antidote developed by Sir Rudolf Peters in the 1940’s used in the treatment of
mercury lead gold and arsenic
in what year did the london smog occur
1952
in which year was the clean air act passed
1956
what did the US delancy clause (1958) state
any substance found to be carcinogenic may not be added to food in the US
what year was the thalidomide disaster in
1961
in which decade was the minimata bay disaster
1960s
which century was the ebers papyrus made in
1500 BC
in what war were poison arrows supposedly used and what century was this
trojan war 1200BC
when was socrates murdered
399BC
what did mithridates VI of Pontus discover in 100BC
a complex mixture of aantidotes known as mithridatium
what was the name of the laws passed which stated that poisoning and sale, purchase and possesion of poisonous substances was illegal, and who were they passed by and when
lex cornelia passed by Sulla in 32BC
when did Nicander of Colophan write the oldest book on the subject to survive from antiquity
1150AD
when did Pietro d’Abano produce “liberde venenis”
1402
who came up with the central dogma of toxicology in 1500
Paracelsus
during which period was poisoning by the Borgia and Medici families for power money and sex a common occurence
renaissance
which scientist performed groundbreaking experiments on snake venoms and plant poisons in 1770
Felice Fontana
in which year did Sir Percival Potts report a high incidence of scrotal cancer in chimney sweeps
1775
who produced a work on the health of workers in 1800
Bernadino Ramazzini
