Animal Toxins Flashcards
which family of snakes inhibit post synaptic transmission
elapid family
which neurotoxins block post synaptic transmission
alpha
how is postsynaptic transmission inhibited
inhibiting acetylcholinesterase
what does black mamba venom contain which blocks post synaptic transmission
fasciculins
which receptor to alpha neurotoxins bind in order to inhibit post synaptic transmission
the nicotinic acetyl cholinereceptor
does the alpha neurotoxin bind the nicotinic acetlycholine receptor with high or low affinity
high
which families of snake inhibit presynaptic inhibition
all 4 families
which type of toxins are involved in presynaptic inhibition
beta
how do beta toxins inhibit presynaptic neurotransmission
block K+ channels and inhibit the release of acetyl choline
what sort of enzymatic activity do beta toxins have
phospholipase A2 activity
how does snake venom cause tissue damage
collogenase, hyaluronidase, metalloproteases
how do the substances in snake venom result in tissue damage
they break down connective tissues at the site of envenomation
how does tissue damage aid the toxin
it promotes adsorption in the body
how can adsorption and distribution be slowed
by immobilizing the patient
what treatment is available for snake venom
antivenom
