Amphetamine Misuse Flashcards
when were amphetamines first synthesised
late 1880s
wat were they used to treat in the 1930’s
cold, asthma, hay fever
why were they used during world war 2
fight fatigue
when was ecstasy/mdma first synthesised
100 years ago
which amphetamine structure is ecstasy based on
cathinone
what toxidrome effects does it cause
sympathomimetic
how does it affect performance for simple tasks
improves
what are the effects
euphoria, enhanced alertness, increased confidence, talkativeness, anorexia
why is there an increased risk of stroke
damage to heart muscles and blood vessels
why can usage lead to cognitive imparement
neurotoxic
what are the adverse effects
amphetamine psychosis, high bp, ventricular fibrilation, hyperthermia, tolerance, addiction
which drug was used as an anti obesity agent
fen-phen
which amphetamines can be used to treat narcolepsy
dexmphetamine
modafinil
how is ephedrine used in medicine
nasal decongestant
what is the mechanism behind the psychostimulant effects
transported into nerve terminal where it increases the release of monoamine neurotransmitters from storage vesicles into the cytoplasm in CNS
