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Farma > Opioides > Flashcards

Opioides Flashcards

1
Q

vida media de la Morfina

A

4-6 horas

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2
Q

se metaboliza por CYP2D6 y es antitusigeno

A

Codeina

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3
Q

mas devil pero mas eficas por via oral que la morfina

A

codeina derivado de la hidrocodona

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4
Q

princial agonista opioide

A

Levorfamol

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5
Q

provoca menos EA que la morfina y actua en todos los receptores opioides

A

Levorfamol

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6
Q

antagonista MOR produce Miosis eleva la FC y lntifica el lavado gastrico puede causar convulsiones

A

Meperidina

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7
Q

inhibe la recaptacion de serotonina mas un IMAO puede causar sd Serotoninergico

A

Meperidina

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8
Q

indicaciones Difenoxilato

A

Antidiarreico agonista MOR

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9
Q

Indicaciones Loperamida

A

Antidiareeico, lentifica la motilidad

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10
Q

usada en adictos para el destete

A

Metadona aliuvia el dolor cronicoterapia heroinomanos

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11
Q

farmaco 100 veces mas potente que la morfina

A

Fentanilo

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12
Q

se usas en Cx cardiovascular o px con insuficiencia cardiaca

A

Fentanilo

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13
Q

usado en dolor postagudo o canceroso EA rigidez muscular

A

Fentanilo

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14
Q

crea metabolito cardiotoxico con AAS

A

Propoxifeno

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15
Q

similar al Tramado EA convulsiones y sindromes Serotoninergicos

A

Tepentadol

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16
Q

inhibe la recaptacion NE y 5HT

A

Tramadol

17
Q

menciona los agonistas antagonistas

A

Buprenorfina, Nalbufina +, Butorfanol y Pentazocina

18
Q

lipofilo de disociacion lenta d erecepores MOR y antagonista K D, aplicado en quemados

A

Buprenorfina

19
Q

Simpaticomimetico a dosis altas y crea sd de abstinencia

A

Nalbufina

20
Q

uso del Butorfanol

A

tx dolor agudo y da sensasion de flotar

21
Q

tx dolor moderado a severo tambien simpaticomimetico y disforico

A

Pentazocina

22
Q

menciona los antagonistas

A

nalaxona y Naltrenaxona

23
Q

uso de la nalaxona

A

aumenta LH,FSH y ACTH, prolactina y disminuye el apetito

24
Q

diferencia entre la nalaxona y la Naltrexona

A

la Naltrexona mas eficas VO y mas potente actua a las 2 hrs

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