Opioid/Opiate Abuse

Question 1

Opioid refers to…

Answer 1

Substance that have the capacity to stimulate opioid receptors.

Question 2

Opioids are also referred to as:

Answer 2

Narcotics/Narcotic Analgesics

Question 3

The standard and it’s derivatives:

Answer 3

Morphine

• Heroin
• Codeine

Question 4

Synthetic analogues to morphine:

Answer 4

Demerol
Pentazocine
Oxycodone

Question 5

This drug is primarily an hypertensive but is used in opioid treatment.

Answer 5

Clonidine

Question 6

It is used because of these properties.

Answer 6

Adrenergic inhibiting properties

Question 7

Clonidine controls symptoms RT..

Answer 7

Autonomich Hyperactivity (N/V/D)

Question 8

T/F Clonidine controls cravings.

Answer 8

FALSE - does not.

Question 9

Dosage of Clonidine?

Answer 9

17mcg per kg of body weight - divided in doses

Question 10

Most common side effects of clonidine are:

Answer 10

Sedation
Dizziness
Dry mouth
Constipe

Question 11

This is an oral opioid that is used to ease opioid withdrawal.

Answer 11

Methodone

Question 12

Methadone is useful for 3 reasons:

Answer 12

Legal to prescribe
Effective orally
Long duration of action (24 hours)

Question 13

Methodone, in principle, is ________ for the _____ and then __________.

Answer 13

Substituted for addictive opioid and gradually withdrawn.

Question 14

Lofty, but substitution and withdrawal can occure over a ____ period.

Answer 14

10 day

Question 15

T/F Methodone is well absorbed in GI.

Answer 15

TRUE

Question 16

Peak plasma levels?

Answer 16

Delayed - 2-6 hours

Question 17

The benefit of methodone is it can be given..

Answer 17

Once a day schedule

Question 18

Dose range starts at

Answer 18

15-20mg, not usually over 40

Question 19

Methodone is sometimes used ____-____ as a _________

Answer 19

Long-term, replacement for illegal drugs

Question 20

These drugs bind to narcotic receptor sites & block euphoria and other effects of opioids (No High man)

Answer 20

Narcotic Antagonists

Question 21

Since they prevent the high, they are useful in:

Answer 21

Preventing relapse

Question 22

This narcotic antagonis, mentioned before, is used for treating alcohol & opioid dependence.

Answer 22

Naltrexone

Question 23

Naltrexone is absorbed…

Answer 23

Rapidly & completely in GI

Question 24

Duration of effect for naltrexone?

Answer 24

24-72 hours

Question 25

Dosages start @ and increase to

Answer 25

25mg - 350 mg/week

Question 26

May be given two ways.

Answer 26

50mg/day or 100mg/3x a week

Question 27

T/F Naltrexone should be give to people who haven’t detoxed.

Answer 27

FALSE - do not give naltrexone before detox is done. Will precipitate rapid withdrawal.

Question 28

Side effects of naltrexone are usually ___related including:

Answer 28

GI Related

N/V/Cramps