Non-benzodiazepines Flashcards

1
Q

Sleepy one. Mom loves it.

A

Zopiclone

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2
Q

Zopiclone is most useful for:

A

Insomnia

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3
Q

Why is zopiclone best for insomnia?

A

Rapid onset & shorter half-life

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4
Q

Zopiclone works by effecting:

A

GABA receptors

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5
Q

Abrupt discontinuance after long-term use will produce:

A

Withdrawal symptoms

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6
Q

Onset of zopiclone?

A

.5-1hour

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7
Q

Peaks in…

A

1.5 hours

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8
Q

Half life of around…

A

5 hours

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9
Q

Dosage of zopiclone? (1-2 tabs) When?

A

3.75-7.5 @ HS

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10
Q

Zopiclone has odd effects on the mouth including:

A

Dry mouth
Coated tongue
Bitter, unpleasant taste

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11
Q

Zopiclone can produce this boozy feeling..

A

Hangover

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12
Q

“I woke up and he was dead officer, I swear”

A

Zopiclone makes for little memory retention after taking.

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13
Q

Zopiclone interacts with…

A

Other CNS depressants

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14
Q

The other non-benzo is…

A

Buspirone

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15
Q

Buspirone is used specifically to treat…

A

Anxiety

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16
Q

The benefit of Buspirone compared to other benzos is:

A

NO TOLERANCE RECOGNIZED

LOW POTENTIAL FOR ABUSE & ABSORPTION

17
Q

T/F Buspirone is useful PRN.

A

False.

18
Q

Buspirone produces its maximum anxiolytic effect in…

A

3-6 weeks

19
Q

Buspirone is also considered remarkably..

A

Safe. Can’t OD on it.

20
Q

Buspirone comes in what preparation?

A

PO

21
Q

T/F Buspirone is rapidly absorbed.

A

TRUE

22
Q

The patient should be informed to do this before taking.

A

Eat - increases absorption by reducing first pass metabolism

23
Q

Peak of buspar?

A

1-1.5hours

24
Q

Half-life?

A

3-11 hours

25
Q

Buspirone is or is not highly protein bound.

A

Is highly protein bound.

26
Q

Dose range for buspirone?

A

5-30mg/day up to 60mg/day

27
Q

Side effects of buspirone are..

A

Minimal but include:
GI upset
Nervousness
Insomnia

28
Q

Taking buspirone with these will elevate blood pressure.

A

MAOI

29
Q

Do not take buspirone with…

A

Other CNS depressants