Opioid Flashcards
Prototype opioid
Morphine
Uses of opioids
euphoria, analgesia, sedation, relief from diarrhea, cough suppression
Opiate
Drug extracted from exudate of the poppy
Opioid
Natural or synthetic drug that binds to opioid receptors producing agonist effects
Narcotic
Term used to characterize pharmacological compoinds used to treat moderate to severe pain
2 naturally occuring opioids
morphine and codeine
3 endogenous opioids
endorphins, enkephalins and dynorphins
Endogenous opioid receptors
Mu1-located outside spinal cord, responsible for central interpretation of pain
Mu2-located throughout CNS. Responsible for supraspinal and spinal analgesia, respiratory depression, constipation, physical dependence and euphoria