Local Anesthesia Flashcards
1
Q
Amides or Esters-Longer half life and longer duration of action
A
Amides. Becasue metabolized in liver
2
Q
Ester metabolism
A
Rapid metabolism by hydrolysis in plasma via ChE and excretion in urine
Short plasma half life (less than 1 min) leads to short duration of action
3
Q
Fiber size vs. minimum anesthetic concentration
A
Big fiber = big Cm
4
Q
pH vs Cm
A
High pH=low Cm
5
Q
Ca concentration vs Cm
A
High Ca = High Cm
6
Q
factors affecting reversal of local anesthesia
A
Absorption into circulation (most important)
Dilution by ECF
Redistribution to other areas
Use of vasoconstrictors
7
Q
Lidocaine
A
Used topically and as an injectable. Most common for epidural going to c section when total motor block desired
8
Q
Dental anesthetic, not NO
A
Articaine
9
Q
Benzocaine
A
Topical only anesthetic
