opiates

Question 1

opiate action

Answer 1

• kill pain by preventing the transmission of pain impulses in the brain rather than at source
• they bind to the opoid receptors in the brain which blocsk the impulses

Question 2

how does a strong analgesic enter the brain

Answer 2

• they have to pass the blood brain barrier; a hydrophobic, non polar environement
  -analgesic properties depend on ;
  ability to move form the blood into the brain where lipid solubility is important

Question 3

morphine

Answer 3

• derived from poppy seed opoium
  0used in sever pain managment
  -can form dependence

Question 4

codeine

Answer 4

• derived from opium or
  METHYLATION reaction of morphine
• ## used in cough medications and sthor term teratment of diarrhoera

Question 5

diamorphine (heroine)

Answer 5

• derived from ESTERIFICATIOn reaction of morphine
• rapidly acting and most abused narcotic
• high euphoric effects/high addiction/high addiction

Question 6

effectiveness of opiate order

Answer 6

increasing analgesic, narcotic and side effects:

1. codiene (least)
2. morphine
3. diamoprhine )most)

Question 7

pain mangemant ladder order

Answer 7

1. use mild analgesic
2. use weak opiod
3. use strong opiod

Question 8

side effects of analgesics

Answer 8

• constipation
• supression of cough reflex
• constriction in pupils
  -narcotic
  -addiction
  = crime and heroine addicts