Anti- Viral Flashcards
virus
- lives in host cell
- rapidly mutates and reproduces
bacteria
- doesnt need host cell; can be extinguished by antibiotics
body immune response
-produce antibodies to atack virus and buil immunity
hiv
(RETROVIRUS); turns RNA into DNA
- releases RNA into cells to create viral DNA
- produces viral particles
- destoryes helper T cells
- mutates rapidly
- lies dormant in cell
treatments
- prophylatic
- antiviral
prophylatics
preventative masure; stimulate body to prepare specific antivodies to the immunity (ACTIVE IMMUNITY)
limits of vaccines; viruses can mutate
antivirals
interfere with the viral life cycle and prevent release of new viral particles from host cell
e.g. alter cell DNA to prevent virus’s multiplication and block enzymatic activity within host cell to stop virus’s multiplication
example: Amantidinel changes he cell membrane to prevent virus entry to host cell; preventative measure
flu virus proteins
hemaglutinin (H); glycoproteins that enables virus to attach to host cell before entering
neuaminididase (N); enzyme that catalyzes a cleavage reaction that allows the virus to release virus particles from host cell to spread infectionsl snips of sialic acid from glycoproteins on host cell surface membrane
flu virus antivirals
- inhibit neuraminidinase or hemaglutinin action and binding
examples:
neuraminidiase inhibitor:
tamiflu and ostalamitvir (0RAL)
-relenza (zanamivir) (INHALATION)