ophthalmology Flashcards
optic neuritis causes (3)
MS
DM
syphilis
optic neuritis features: (5)
unilateral decrease in visual acuity over hours or days
poor discrimination of colours, ‘red desaturation’
pain worse on eye movement
relative afferent pupillary defect
central scotoma
optic neuritis mgt
high dose steroids
(usually resolved in 4-6 weeks)
sinister cause of chronic unilateral conjunctivitis
orbital lymphoma
bacterial conjunctivitis features:
Purulent discharge
Eyes may be ‘stuck together’ in the morning)
viral conjunctivitis features:
Serous discharge
Recent URTI
Preauricular lymph nodes
bacterial conjunctivitis mgt:
chloramphenicol
fusidic acid in pregnant
sudden loss of vision causes: (4)
ischaemic/vascular
vitreous haemorrhage
retinal detachment
retinal migraine
HSV keratitis presentation: (5)
DENDRITIC CORNEAL ULCER
red, painful eye
photophobia
epiphora (watery eyes)
visual acuity may be decreased
fluorescein staining may show an epithelial ulcer
HSV keratitis mgt
topical aciclovir
immediate ophthalmology r/v
rheumatoid arthritis ocular manifestations (5)
keratoconjunctivitis sicca (= dry eyes, most common)
episcleritis (erythema)
scleritis (erythema and pain)
corneal ulceration
keratitis
acute angle closure glaucoma
what happens?
rise in IOP secondary to an impairment of aqueous outflow
acute angle closure glaucoma predisposing factors: (3)
hypermetropia (long-sightedness)
pupillary dilatation
lens growth associated with age
acute angle closure glaucoma
features: (7)
severe pain: may be ocular or headache
decreased visual acuity
symptoms worse with mydriasis (e.g. watching TV in a dark room)
hard, red-eye
haloes around lights
semi-dilated non-reacting pupil
corneal oedema results in dull or hazy cornea
systemic upset may be seen, such as nausea and vomiting and even abdominal pain
acute angle closure glaucoma mgt
- offer 360° selective laser trabeculoplasty (SLT) first-line to people with an IOP of ≥ 24 mmHg
- prostaglandin analogue (PGA) eyedrops should be used next-line
- BB eye drops
carbonic anhydrase inhibitor eye drops
sympathomimetic eye drops - surgery in the form of a trabeculectomy may be considered in refractory cases.
prostaglandin analogues
mode of action
Increases uveoscleral outflow
prostaglandin analogues
example:
lantoprost
prostaglandin analogues
SE:
brown pigmentation of the iris
increased eyelash length
BB
examples:
timolol
betaxolol
BB mode of action
Reduces aqueous production
groups to avoid BB in:
asthmatics
heart block
Sympathomimetics
examples:
e.g. brimonidine, an alpha2-adrenoceptor agonist)
Sympathomimetics
mode of action:
reduces aqueous production and increases outflow
Sympathomimetics
who should avoid:
Avoid if taking MAOI or tricyclic antidepressants
Carbonic anhydrase inhibitors
example:
Dorzolamide
Carbonic anhydrase inhibitors
mode of action:
Reduces aqueous production
Carbonic anhydrase inhibitors
SE:
Systemic absorption may cause sulphonamide-like reactions
miotics
e.g.
ilocarpine, a muscarinic receptor agonist
miotics mechanism:
Increases uveoscleral outflow