Oo genesis Flashcards

1
Q

What is oogenesis

A

formation of the female gamete

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does oogenesis start from

A

Undifferentiated primordial germ cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How many copies of chromosomes do primordial germ cells have?

A

2 copies (diploid)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are diploid cells

A

2 homologs of each chromosome, one from each parent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What must happen prior to fertilization for the diploid cell to be produced

A

number of chromosomes must be reduced, haploid cells must be made

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What happens during mitosis

A

two identical cells are produced

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the 5 stages of prophase 1

A
Leptotene
zygotene
pachytene
diplotene
diakinesis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What happens during Leptotene

A

chromosomes appear as thin threads

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What happens during zygotene

A

Condensation of threads

Synapsis directed by the synaptonemal complex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What happens during pachytene

A

genetic rcombination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What hapens during diplotene

A

Homologs start to separate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What happens during diakinesis

A

centromers move away from each other

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What happens during metaphase 1

A

homologs align equidistant to each other

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What happpens during anaphase 1

A

Homologs are separated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What happens during telophase 1

A

two daughter cells are formed

Each daughter cell contains one copy fo the homologous chromosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How do oogoni multiply

A

Mitosis

17
Q

When is meiosis arrested

A

Late diplotene stage (dictyate)

18
Q

When does meiosis resume

A

until activation of the oocyte in response to ovulatory gonadotropic stimulus

19
Q

What is a primoridal follicle

A

oocyte enclosed by single layer of pregranulosa cells

20
Q

When is the 2nd meiotic division arrested

A

metaphase 2

21
Q

when does the 2nd meiotic division resume

A

fertilization

22
Q

What is folliculogenesis

A

formation of an antral follicle starting from a primordial follicle

23
Q

what is a follicle

A

oocyte surrounded by somatic cells

24
Q

Do primary and secondary follicles need gonadotropins

A

no

25
Q

What does development beyond secondary follicles require

A

gonadotropins

26
Q

What does FSH do

A

stimulate follicular growth

27
Q

what does LH do

A

maturation of oocyte

triggers ovulation

28
Q

What is the two cell two gonadotropin hypothesis

A

LH: Theca cell turns cholesterol to androgen
FSH: Granulosa cell, turns androgen into estrogen

29
Q

What is the only positive feedback loop

A

Estrogen on the hypothalamus/GnRH once it reaches threshold

30
Q

What happens when estrogen reaches threshold

A

Burst of GnRH
Surge of LH
follicular maturation and ovulation

31
Q

what does the LH surge do to meiosis

A

causes it to resume (first polar body extruded)

32
Q

what do the theca cells do after the LH surge

A

produce low levels of progesterone

33
Q

What happens to progesterone levels during CL formation

A

slowly increase

34
Q

What is progesterone required for

A

maintenance of pregnancy

35
Q

What causes the CL to regress in large animals

A

PGF2alpha

36
Q

What does the CL become after its destruction

A

corpus albicans