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Repro > Just the tip- sex determination > Flashcards

Just the tip- sex determination Flashcards

1
Q

What are the 3 stages of sexual differentiation

A

Chromosomal
Gonadal
Phenotypic

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2
Q

What is SRY

A

The sex determining region gene for males

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3
Q

What drives gonadal differentiation

A

Chromosomal sex

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4
Q

What is the precursor of the gonad

A

gonadal ridge

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5
Q

What are gamets

A

Primordial germ cells

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6
Q

Where do Primordial germ cells originate from

A

yolk sac

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7
Q

Where do primordial germ cells migrate to

A

gonadal ridge

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8
Q

What is the gonadal ridge precursor to

A

gonad

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9
Q

What gene differentiates the testies

A

SRY gene

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10
Q

What causes ovarian differentiation

A

Two copies of key genes

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11
Q

In males what do sex chords give rise to

A

seminiferous tubules

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12
Q

What do sertoli cells produce

A

Anti-Mullerian Hormone

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13
Q

What do primordial germ cells give rise to in males

A

spermatozoa

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14
Q

What do Leyding cells produce

A

Testosterone

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15
Q

What do primordial germ cells give rise to in females

A

oocytes

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16
Q

What are the two duct systems present in the early embryo regardless of chromosomal sex

A 
Mesonephric duct (Wolffian)
Paramesonephric (Mullerian)
17
Q

What determines the development of the tubular tract

A

Presence or absence of testicular hormones

18
Q

What is testosterone essential for

A

Development of male duct system (mesonephric)

19
Q

What is Ant-Mullerian hormone cause

A

regression of female duct system (paramesonephric)

20
Q

What do the mesonephric ducts become

A

Epidiymides, deferent ducts, urethra

21
Q

What do the paramesonephric ducts become

A

oviducts, uterus, cervix, cranial vagina

22
Q

What is the main determinate of phenotypic sex

A

dihydrotestosterone (DHT)

23
Q

What do genital tubercles become in the presence/absence of DHT

A

PENIS/clitoris

24
Q

What do genital swellings become in the presence/absence of DHT

A

Scrotum/vulva

25
Q

What do genital folds do in the presence/absence of DHT

A

Close/No close

Repro (13 decks)

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