Online Med Ed Lecture 1 Flashcards
What are two complications caused of sickle cell, big picture?
Vaso occlusion leading to ischemia and hemolysis
What are the two complications because of the hemolysis in sickle cell?
Rise in bilirubin, leading to jaundice and gall stones
Anemia leading to kidneys releasing EPO and rise in reticulocytes to boost RBC number
What do we need to sometimes give sickle cell patients when they are getting transfusions and why?
Deferoxamine to chelate all the iron in the transfusions
What two organs are most commonly affected by chronic ischemia in sickle cell and what is the result and how do we treat it?
Spleen, auto infarcts and vulnerable to encapsulated organism. give prophylaxis penicillin until age 5.
Bone, leading to osteomyelitis because of staph. Now is you see salmonella, you are thinking sickle cell patient. Avascular necrosis of the hip. Conservative treatment first, and then maybe surgery.
What are the two organs and then conditions affected by acute ischemia due to sickle cells?
Stroke and acute chest syndrome.
Exchange transfusions.
4 lab values/patient presentation for most sickle cell patients?
Anemic (low HgB), elevated bilirubin, elevated reticulocyte count, pain
Treat and prevent vaso occlusive crisis?
Treat with fluids, o2, and pain meds
Prevent with hydroxyurea
2 ways to diagnose sickle cell?
Worst variation of sickle cell?
Blood smear and electrophoresis
Sbeta0
What usually causes Congential cataracts at birth and after birth?
TORCH infection
Galactosemia, sorbitol
In what setting would we see retinopathy of prematurity?
Premature baby where the lungs haven’t developed yet and they need high levels of FI02 which will cause the retinopathy.
At what day does gonorrhea conjunctivitis present in a baby, is discharge bilateral or unilateral, and what is treatment?
2-7
Bilateral
Ceftriaxone
At what day does chlamydia conjunctivitis present in a baby, is discharge bilateral or unilateral, and what is treatment?
5-14, unilateral, oral erythromycin
What to treat Herpes STD?
Acyclovir
At what age do the following conditions present?
DDH, legg calve perthes, slipped capital femoral epiphysis, septic joint, transient synovitis, osgood slaughters, scoliosis?
Newborn, 6, 11-13, any age, any age, teenage athletes, teenage girl
What type of x ray for slipped capital femoral?
Frog leg