Oncology

Question 1

What is given for neutropenic sepsis prophylaxis during and post chemotherapy?

Answer 1

Ciprofloxacin

Question 2

What medical treatment is given for spinal cord compression?

Answer 2

Dexamethasone

Question 3

What four treatments can be used for hypercalcaemia?

Answer 3

IV saline
Bisphosphonates
Calcitonin
Denosumab (rank inhibitor)

Question 4

What may be seen on ECG in hypercalcaemia?

Answer 4

Short QT interval

Question 5

What type of reaction is anaphylaxis?

Answer 5

Type 1 hypersensitivity IgE mediated

Question 6

How is raised ICP treated?

Answer 6

Dexamethasone
Mannitol
Surgical intervention

Question 7

What antigen marker is most commonly raised in bowel cancer?

Answer 7

Carcinoembryonic antigen (CEA)

Question 8

Which lymph nodes do testicular tumours typically metastasise to? (1)

Answer 8

Para-aortic

Question 9

What are the tumour markers used to monitor treatment response in testicular cancer? (2)

Answer 9

Alpha feto protein

Beta HCG

Question 10

Name some risk factors for developing testicular cancer? (4)

Answer 10

Male sex
Undescended testes 
Klinefelters
Tall height
Young paternal and young maternal age
Male infertility

Question 11

What cancers is the tumour marker CA 19-9 associated with? (2)

Answer 11

Pancreatic cancer and biliary duct cancers

Question 12

What cancers is the tumour marker alpha fetoprotein associated with? (2)

Answer 12

Hepatocellular carcinoma

Germ cell ovarian and testicular cancers

Question 13

What is the management for neutropenic sepsis? (4)

Answer 13

ABCDE
Tazocin + Vancomycin
Ganulocyte colony stimulating factor
Clotting and FBC - for monitoring and differentiating from DIC

Question 14

What is the diagnostic criteria for neutropenic sepsis? (2)

Answer 14

Neutrophils <500 cells per microlitre

Temp >38.3