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Finals > Oncology > Flashcards

Oncology Flashcards

1
Q

side effect of cyclophosphamide

A

haemorrhagic cystitis

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2
Q

which class of chemo are MTX and 5-FU

A

antimetabolites

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3
Q

drug for anticipatory n&v

A

lorazepam

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4
Q

chemo drug that causes lung fibrosis

A

bleomycin

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5
Q

side effect of vincristine and cisplatin

A

peripheral neuropathy

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6
Q

doxorubicin s/e

A

cardiomyopathy

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7
Q

Preferred pain relief in CKD (3)

A

alfentanil
fentanyl
buprenorphine

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8
Q

BRC2 association in men

A

prostate cancer

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9
Q

Management of malignant hypercalcaemia

A

rehydrate first
IV bisphosphonates eg pamidronate - but this takes up to a week to work
Can give calcitonin in the meantime

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10
Q

Hypercalcemia - avoid which diuretic

A

thiazide

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11
Q

Presentation of spinal cord compression

A

Band like sharp pain - worse on coughing/straining
weakness
altered sensation
bowel/bladder dysfunction

Majority in T spine

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12
Q

Ix for spinal cord compression

A

urgent MRI

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13
Q

Rx spinal cord compression

A

dexamethasone - holding measure
potentially surgery
(single vertebral area, no widespread mets, radio resistant…)
radiotherapy

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14
Q

SVCO usually due to ? cancer

A

lung

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15
Q

symptoms of SVCO

A 
distended veins
dyspnoea
oedema
headache
*usually worsened by bending forwards or lying down*
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16
Q

Ix SVCO

A

CXR

CT thorax

17
Q

Rx SVCO

A

depends if its caused by clot or extrinsic compression
clot > thrombolyse

extrinsic > stent for rapid relief (but doesn’t treat cause); steroids; chemo

18
Q

Presentation of pericardial tamponade

A

SOB, fatigue, palpitations, tachycardic
Pulsus paradoxus
becks triad - muffled heart sounds, rising JVP, falling BP

19
Q

what is the presentation of cardiac tamponade similar to

A

constrictive pericarditis

20
Q

pulsus paradoxus

A

> 10 mmHg drop in BP on inspiration

21
Q

neutropenic sepsis definition

A

neutrophils <0.5 or <1 if had chemo in last 21 days

22
Q

what can be used for symptom relief in cerebral oedema

A

mannitol

23
Q

in what types of cancer does tumour lysis syndrome occur

A

leukaemia and lymphomas

24
Q

tumour lysis syndrome

A 
rapid tumour breakdown causing release of chemicals 
>>
AKI 
high potassium, phosphate and uric acid
low calcium
25
Q

tumour lysis syndrome

A 
rapid tumour breakdown causing release of chemicals 
>>
AKI 
high potassium, phosphate and uric acid
low calcium
26
Q

prevention of TLS

A

allopurinol and good hydration starts 24h before chemo

27
Q

management of radio induced cystitis

A

fluids

NSAIDs

Finals (15 decks)

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