MS Flashcards
1
Q
diagnostic criteria
A
McDonald criteria:
2+ attacks & 2+ objective clinical lesions
OR
2+ attacks & 1 objective clinical lesion AND MRI/LP evidence
2
Q
symmetrical?
A
not usually
3
Q
RR - acute attacks last about
A
1-2 months
4
Q
primary progressive - progression > ?
A
1 year
5
Q
acute relapse tx
A
methylprednisolone
IV/high dose oral
3-5 days
6
Q
what tx is only used in rapidly evolving severe MS and why
A
natalizumab (tysabri)
link to progressive multifocal leukoencephalopathy
(caused by JC virus)
7
Q
rare associations with alemtuzumab
A
stroke
arterial dissection
8
Q
MRI frequency
A
annually
