oncology

Question 1

large peripheral lung mass - which cancer type?

Answer 1

large cell carcinoma

Question 2

cavitary lesion in a bronchus - which cancer type?

Answer 2

squamous cell cardinom

Question 3

which lung ca assoc w/hypercalcemia?

Answer 3

squamous cell carcinoma

Question 4

why hypercalcemia in squamous cell lung ca?

Answer 4

increased PTH production

Question 5

hilar lung mass - which cancer?

Answer 5

small cell carcinoma

Question 6

Pancoast syndrome - what is it?

Answer 6

• shoulder pain
• Horner’s syndrome
• hand muscle atrophy and weakness

Question 7

JAK2 mutation is associated with which dz?

Answer 7

polycythemia vera

Question 8

renal insufficiency in multiple myeloma - what is the etiology?

Answer 8

• light chain cast nephropathy

- light chain deposition dz

Question 9

symptoms of hyperviscosity syndrome in multiple myeloma?

Answer 9

• nasal/oral bleeding
• blurry vision
• confusion/headache
• heart failure

Question 10

treatment of hyperviscosity syndrome in MM?

Answer 10

plasmapheresis if symptomatic

Question 11

which cancer is DIC most commonly associated with?

Answer 11

acute leukemia

Question 12

what does trastuzumab target?

Answer 12

HER2

Question 13

cancers that commonly metastasize to the spinal column?

Answer 13

• prostate
• breast
• lung
• non-Hodgkins
• renal cell carcinoma

Question 14

lobular cardinoma in situ - next step?

Answer 14

excisional biopsy (LCIS is benign, but often upstaged to DCIS when excisional bx is done)

Question 15

who should be tested for BRCA mutation?

Answer 15

• first degree relative w/bilateral breast cancer
• first degree relative w/breast + ovarian cancer
• mult first degree relatives w/breast cancer
• male relative w/breast cancer

Question 16

whatn risk factor make you screen earlier for breast cancer?

Answer 16

• 2 first degree relatives (one <50 yo) w/breast cancer
• 3+ first or 2nd degree relatives w/breast cancer
• 1st or 2nd degree relative w/breast + ovarian cancer
• first degree w/bilateral breast cancer
• breast ca in male relative

Question 17

breast ca screening - timing recommendations for general pop?

Answer 17

• every 2 years

- age 50-75

Question 18

leading cause of death in survivors of Hodgkin Lymphoma?

Answer 18

secondary malignancy

• • breast
• • lung
• • GI
• • acute leukemia
• • non-Hodgkin

Question 19

tumor makers for testiular cancer?

Answer 19

• AFP

- B hcg

Question 20

who to screen for lung ca?

Answer 20

• Age 55-80
• 30+ pack years
• smoked w/in past 15 years