dermatology Flashcards
acanthosis nigricans - assoc w/what 2 diseases?
- DM
- GI malignancy
porphyria cutanea tarda - assoc w/ which dz?
hep c
cutaneous leukoclastic vasculitis (palpable purpura) 2/2 cryoglobulinemia - assoc w/which dz?
hep c
dermatitis herpetiformis - assoc w/which dz?
celiac dz
sudden onset psoriasis, recurrent herpes, disseminated molluscum - assoc w/which dz?
HIV
severe seborrheic dermatitis - assoc w/which 2 dz?
- HIV
- parkinson
explosive onset of multiple itchy, seborrheic keratoses - assoc w/which dz?
GI malignanct
pyoderma gangrenosum - assoc w/which dz?
IBD
tense bullae - which skin dz?
bullous pemphigoid
flaccid bullae - which dz?
pemphigus vulgaris
rash w/severe itching, assoc w/celiac dz?
dermatitis herpetiformis
bullous pemphigoid - tx?
topical high-potency steroids (if more severe, need oral)
hypopigmented spots w/fam hx of deafness - dx?
NF-2 (autosomal dominant)
hyperpigmented cafe au lait spots - dx?
NF-1
what is cause of deafness in NF-1 and NF-2
acoustic neuroma
hypopigmented maculae (Ask leaf spots), glial proliferation, several organ hamartomas - dx?
tuberous sclerosis
facial port-wine stain and leptomeningeal aniomatosis - dx?
Sturge-Weber syndrome
multiple telangiectasias and vascular lesions on CNS - dx?
Osler-Rendu-Weber syndrome
cherry red spot on macula on fundoscopic exam - dx?
central retinal artery occlusion
common causes of central retinal artery occlusion?
- carotid atherosclerosis
- cardiac embolism
- small vessel disease (htn, DM)
- vasculitis (GCA)
urgent tx of central retinal artery occlusion?
LOWER INTRAOCULAR PRESSURE
- ocular massage
- anterior chamber paracentesis
- IV acetazolamide
- IV mannitol
severe eye pain, vision loss, HA, nausea, vomiting, light halos, dx?
acute angle closure glaucoma
acute or subacute vision loss w/tortuous and dilated veins, diffuse hemorrhages, disk swelling, cotton wool spots on exam - dx?
central retinal vein occlusion
peripheral then central vision loss, then shower of floaters - dx?
retinal detachment
erythrasma - what is it? what causes it
- superficial skin infection of intertriginous areas (thin, erythematous)
- corynebacterium minutissumum
tinea cruris - what causes it?
trichophyton rubrum
intertrigo - what causes it?
candida
ecthyma ganrenosum - what causes it?
pseudomonas aeruginosa
mycosis fungoides - what is it?
cutaneous T-cell lymphoma that causes slowly progressive skin lesions (patches, plaques, tumors, erythroderma)
pyoderma gangrenosum - what is it?
neutrophilic dermatosis assoc w.IBD or athritis
- start as inflammatory nodules/pustules/vesicles –> evolve into ulcers
ecthyma gangrenosum - presentation?
redness, pustule, nonpainful, ruptures, ulcer, necosis of center
erythrasma - what is it? what causes it?
infection of intertriginous spaces caused by corynebacterium minutissimum = pruritic, reddish brown, finely wrinkled papules
treatment for cutaneous T cell lymphoma?
interferon alpha
actinic keratoses - treatment?
fluorouracil
pruritic, polygonal, violaceous, papules or plaques on flexural surfaces - dx?
lichen planus
dermatomyositis - which antibodies associated?
- anti-RNP
- anti-Jo
- anti-Mi2
dermatomyositis - extramuscular findings?
- interstitial lung dz
- dysphagia
- myocarditis
explosive onset of multiple itchy seborrheic keratoses - dx?
GI malignancy
pyoderma gangrenosum - assoc w/what systemic dz?
inflammtory bowel disease
sudden onset severe psoriasis - dx?
HIV
sudden onset severe seborrheic dermatitis - dx?
HIV
lichen planus - associated w/which systemic dz?
hep C
porphyria cutanea tarda - assoc w.what systemic dissease?
hep C
leukocytoclastic vasculitis - assoc w/what systemic dz?
hep C
chalazion - what is it?
granulomatous inflammation of meibomin gland –> pea sized nodule in eyelid
rosacea - tx?
- brimodine
- if pustular –> topical metronidazole or azalaic acid
- if refractory –> oral abx
actinic keratoses –> can transofrm into what?
squamous cell carcinoma
lichen simplex chronicus - what is it?
thickened excoriated plaques 2/2 persistent scratching and rubbing
what use on sensitive areas w/eczema (face, eyelids)?
calcineurin inhibitors (tacrolimus)
agents for field therapy for pts with lots of actinic keratoses?
- 5-FU
- topical diclofenac
- imiquimod
“cherry red spot” on fundus exam - dx?
central retinal artery occlusion
fundus w/retinal hemorrhages + optic disc edema (blood + thunder) - dx?
central retinal vein occlusion
fundus w/vitreous hemorrhage + elevation of retina - dx?
retinal detachment
decreased red reflex + visible hemorrhage on fundoscopy - dx?
vitreous hemorrhage
monocular vision loss, eye pain, headache, n/v, conjunctival erythema - dx?
acute angle-closure glaucoma
monocular vision loss, eye pain that worsens with eye movement - dx?
optic neuritis