gastroenterology Flashcards
SAAG - calculation?
serum albumin - ascites albumin
SAAG - what does it tell us?
> = 1.1 : high albumin gradient, indicates portal htn
<1.1 : low albumin gradient, indicates no portal htn
conditions associated w/high SAAG?
- CHF
- cirrhosis
- EtOH hepatitis
conditions associated w/low SAAG?
- peritoneal carcinomatosis
- peritoneal TB
- nephrotic syndrome
- pancreatitis
- serositis
Gilbert syndrome
impaired hepatic conjugation, results in isolated indirect hyperbili
isolated anti-HBc - what are the 3 scenarios?
- acute hepatitis B (anti-HBsAg has fallen, anti-HBs has not yet risen)
- years after recovery from acute HBV once anti-HBs has waned off
- chronic HBV infection when HBSAg has fallen off
if isolated anti-HBc, what send next?
- IgM anti-HBc to see if infection is recent (ie in window period)
- LFTs
does HBV vaccine cause rise in core antibody?
NO only surface antibody
what abx to start for SBP?
cefotaxime
flexible sigmoidscopy should be repeated every __ years if normal?
5
flex sig w/stool testing (YEARLY) should be repeated every __ years if normal?
10
most common auto-antibodies in autoimmune hepatitis?
- ANA
- anti-smooth muscle ab
primary biliary cirrhosis - which auto-antibody?
anti-mitochondrial
what is LFT pattern in primary biliary cirrhosis?
elevated alk phos
if pregnant pt develops biliary colic unresponsive to supportive care, can do cholecystectomy?
yes, in 2nd trimester
gallbladder wall calcifications - significance?
= porcelain gallbladder
- increased risk gallbladder cancer
- need prophylactic chole
charcot triad for cholangitis?
- fever
- jaundice
- RUQ pain
