ONCOLOGY Flashcards

1
Q

The nurse is monitoing a child for bleeding after surgery for removal of a brain tumour. The nurse checks the head dressing for the presence of blood and notes a colourless drainage on the back of the dressing. Which intervention should be done immediately?
A/ Reinforce the dressing
B/ Notify the HCP
C/ Document the findings and continue to monitor
D/ Circle the area of drainage and continue to monitor

A

B/ Notify the HCP

Colourless drainage after a craniotomy indicates the presence of CSF and should be reported ASAP to the HCP.

Options 1,2,3 are not immediate nursing interventions

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2
Q

A child undergoes surgery to remove a brain tumour. During the post-op period, the nurse is monitoring the child and notes that the child is restless, tachycardic, and they are hypotensive compared to their baseline value. Nurse suspects the child is in shock, which is the most appropriate nursing action?
A/ Notify the HCP
B/ Place child in supine position
C/ Place child in Trendelenburg’s Position
D/ Increase the flow rate of the IV fluids

A

A/ Notify the HCP

In the event of shock, the HCP is notified immediately before the nurse intervenes.

After craniotomy, NEVER place anyone in a Trendelenburg’s position as this will significantly increase ICP!

The head of the bed should be elevated not lowered

Increasing IV fluids can increase ICP

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3
Q

Which of the following is incorrect in relation to osteosrcomas in children and adolescents?
A/ The femur is the most common site of this sarcoma
B/ The child dose not experience any pain at the site of the tumour
C/ Limping, if weight-bearing limb is affects is a clinical manifestation
D/ The symptoms of the disease in the early stage are almost always attributed to growing pains

A

B/ No pain

Most common bone cancer in kids and typically occurs in the metaphysis of long bones, especially in lower extremities (Femur mostly)

Manifested by progressive, insidious and intermittent pain at the tumour site.

Other options are all correct

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4
Q

The nurse analyzes the laboratory values of a child with leukaemia who is receiving chemotherapy. The nurse notes that the platelet count is 19,500 cells/mm3. On the basis of this laboratory result, which intervention should the nurse include in the plan of care?
A/ Initiate Bleeding precautions
B/ Monitor closely for signs of infection
C/ Administration of Anticoagulants q12h
D/ Initiate protective isolation precautions

A

A/ BLEEDING

Leukemia is a malignant increase in the number of leukocytes. Affecting bone marrow, causing anemia from decreased erythrocytes, infections from neutopenia, and bleeding from decreased platelet production.

A severely thrombocytopenic child has a platelet count of less than 20,000 cells/mm3, so bleeding precautions must be started.

They do not need anticoagulants.

The other options are more related to prevention of infection.

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5
Q

A 15-year old has been admitted to the hospital with Acute Lymphocytic leukaemia. Which signs and symptoms require the most immediate nursing intervention?
A/ Fatigue and Anorexia
B/ Fever and Petechiae
C/ Swollen lymph nodes in the neck and lethargy
D/ Enlarged liver and spleen

A

B/ Fever and Petechiae

This indicates a suppression of normal WBCs and thrombocytes by the bone marrow and put the client at risk for other infections and bleeding.

Fatigue is a common symptom of Acute Lymphocytic leukaemia

Swollen glands and lethargy are uncomfortable, but do not require immediate attention. Enlarged liver and spleen require safety precautions that prevent injury to the abdomen, but this is not the priority

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6
Q

After teaching the parents of a child newly diagnosed with Leukaemia about the disease, which response from the parents indicates that they understand the nature of leukaemia?
A/ The disease is in infection resulting in increased white blood cell production
B/ The disease is a type of cancer than increases the amount of immature white blood cells
C/ The disease is an inflammation associated with enlargement of the lymph nodes
D/ The disease is a type of cancer that decreases the amount of white blood cells circulating in the lymphatic system

A

B/ Immature WBCs

Is a neoplastic/cancerous disorder that is characterized by the proliferation of immature WBCs.

It is not an infection or inflammation

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7
Q
Which medication prescription for a child with leukaemia should the nurse question?
A/ Hydromorphone
B/ Acetaminophen with codeine
C/ Ibuprofen
D/ Acetaminophen with hydrocodone
A

C/ Ibuprofen

Ibuprofen increases bleeding time and is contraindicated in clients with leukaemia. Non-narcotic drugs other than Ibuprofen and ASA, such as Tylenol, may be used to control pain and may be used in combination with narcotics like codeine or hydromorphone or hydrocodone.

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8
Q
Which signs and symptoms of leukaemia would the nurse suspect the client has developed thrombocytopenia?
SELECT ALL THAT APPLY
A/ Fever
B/ Petechiae
C/ Epistaxis
D/ Anorexia
E/ Bone Pain
F/ Shortness of Breath
A

B/ Petechiae
C/ Epistaxis

Acute Lymphocytic leukaemia causes a decrease in platelets, RBCs, and WBCs due to the unrestricted proliferation of immature WBCs. Chemotherapy is used to treat leukaemia, however this increases thrombocytopenia, neutropenia, and anemia. Thus these patients are at an increased risk of bleeding; so petechiae (small red-purple bruises under the skin) and epistaxis (nosebleeds) are a clinical sign.

Fever is the result of neutropenia

Anorexia and shortness of breath is due to anemia

Bone pain is related to unrestricted proliferation of WBCs

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9
Q

The nurse is reviewing the laboratory results of a client diagnosed with multiple myeloma. Which would the nurse expect to note specifically in this disorder?
A/ Increased calcium level
B/ Increased white blood cells
C/ Decreased blood urea nitrogen level
D/ Decreased number of plasma cells in the bone marrow

A

A/ Increased calcium level

Findings indicative of multiple myeloma are an INCREASED number of plasma cells in the bone marrow, anemia, hypercalcemia caused by the release of calcium from the deteriorating bone tissue, and an elevated blood urea nitrogen level. An increased white blood cell count may or may not be present and is not related specifically to multiple myeloma.

*read question carefully

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10
Q
The nurse is developing a plan of care for the client with multiple myeloma and includes which priority intervention in the plan?
A/ Encouraging fluids
B/ Providing frequent oral care
C/ Coughing and deep breathing
D/ Monitoring the red blood cell count
A

A/ Encouraging fluids

Hypercalcemia caused by bone destruction is a priority concern in the client with multiple myeloma. The nurse should administer fluids in adequate amounts to maintain a urine output of 1.5 to 2 L/day; this requires about 3 L of fluid intake per day. The fluid is needed not only to dilute the calcium overload but also to prevent protein from precipitating in the renal tubules. Options 2, 3, and 4 may be components of the plan of care but are not the priority in this client.

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11
Q

When caring for a client with an internal radiation implant, the nurse should observe which principles? SELECT ALL THAT APPLY

  1. Limiting the time with the client to 1 hour per shift.
  2. Keeping pregnant women out of the client’s room.
  3. Placing the client in a private room with a private bath.
  4. Wearing a lead shield when providing direct client care.
  5. Removing the dosimeter film badge when entering the client’s room.
  6. Allowing individuals younger than 16 years old in the room as long as they are 6 feet away
    from the client.
A
  1. Keeping pregnant women out of the client’s room.
  2. Placing the client in a private room with a private bath.
  3. Wearing a lead shield when providing direct client care.

The time that the nurse spends in a room of a client with an internal radiation implant is 30 minutes per 8-hour shift. The client must be placed in a private room with a private bath. The nurse should wear a lead shield to reduce the transmission of radiation. The dosimeter film badge must be worn when in the client’s room. Children younger than 16 years of age and pregnant women are not allowed in the client’s room.

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12
Q

While giving care to a client with an internal cervical radiation implant, the nurse finds the

implant in the bed. The nurse should take which initial action?
A/ Call the health care provider (HCP).
B/ Reinsert the implant into the vagina.
C/ Pick up the implant with gloved hands and flush it down the toilet.
D/ Pick up the implant with long-handled forceps and place it in a lead container.

A

D/ Pick up the implant with long-handled forceps and place it in a lead container.

In the event that a radiation source becomes dislodged, the nurse would first encourage the client to lie still until the radioactive source has been placed in a safe closed container. The nurse would use a long-handled forceps to place the source in the lead container that should be in the client’s room. The nurse should then call the radiation oncologist and then document the event and the actions taken. It is not within the scope of nursing practice to insert a radiation implant.

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13
Q

The home health care nurse is caring for a client with cancer who is complaining of acute pain. The most appropriate determination of the client’s pain should include which assessment?
A/ The client’s pain rating
B/ Nonverbal cues from the client
C/ The nurse’s impression of the client’s pain
D/ Pain relief after appropriate nursing intervention

A

A/ The client’s pain rating

The client’s self-report is a critical component of pain assessment. The nurse should ask the client to describe the pain and listen carefully to the words the client uses to describe the pain. Nonverbal cues from the client are important but are not the most appropriate pain assessment measure.

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14
Q
A client is admitted to the hospital with a suspected diagnosis of Hodgkin’s disease. Which assessment finding would the nurse expect to note specifically in the client?
A/ Fatigue
B/ Weakness
C/ Weight gain
D/ Enlarged lymph nodes
A

D/ Enlarged lymph nodes

Hodgkin’s disease is a chronic progressive neoplastic disorder of lymphoid tissue characterized by the painless enlargement of lymph nodes with progression to extralymphatic sites, such as the spleen and liver. Weight loss is most likely to be noted. Fatigue and weakness may occur but are not related significantly to the disease.

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15
Q
During the admission assessment of a client with advanced ovarian cancer, the nurse recognizes which symptom as typical of the disease?
A/ Diarrhea
B/ Hypermenorrhea
C/ Abnormal bleeding 
D/ Abdominal distention
A

D/ Abdominal distention

Clinical manifestations of ovarian cancer include abdominal distention, urinary frequency and urgency, pleural effusion, malnutrition, pain from pressure caused by the growing tumour and the effects of urinary or bowel obstruction, constipation, ascites with dyspnea, and ultimately general severe pain. Abnormal bleeding, often resulting in hypermenorrhea, is associated with uterine cancer.

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16
Q

The nurse is caring for a client with bladder cancer and bone metastasis. What signs/symptoms would the nurse recognize as indications of a possible oncological emergency? SELECT ALL THAT APPLY

  1. Facial edema in the morning
  2. Serum calcium level of 12 mg/dL
  3. Weight loss of 20 lb in 1 month
  4. Serum sodium level of 136 mg/dL
  5. Serum potassium level of 3.4 mg/dL
  6. Numbness and tingling of the lower extremities
A
  1. Facial edema in the morning
  2. Serum calcium level of 12 mg/dL
  3. Numbness and tingling of the lower extremities

Oncological emergencies include sepsis, disseminated intravascular coagulation, syndrome of inappropriate antidiuretic hormone, spinal cord compression, hypercalcemia, superior vena cava syndrome, and tumor lysis syndrome. Blockage of blood flow to the venous system of the head resulting in facial edema is a sign of superior vena cava syndrome. A serum calcium level of 12 mg/dL indicates hypercalcemia. Numbness and tingling of the lower extremities could be a sign of spinal cord compression. Mild hypokalemia and weight loss are not oncological emergencies. A sodium level of 136 mg/dL is a normal level.

17
Q

A client is diagnosed with multiple myeloma and the client asks the nurse about the diagnosis. The nurse bases the response on which description of this disorder?
A/ Altered red blood cell production
B/ Altered production of lymph nodes
C/ Malignant exacerbation in the number of leukocytes
D/ Malignant proliferation of plasma cells within the bone

A

D/ Malignant proliferation of plasma cells within the bone

Multiple myeloma is a B-cell neoplastic condition characterized by abnormal malignant proliferation of plasma cells and the accumulation of mature plasma cells in the bone marrow. Options 1 and 2 are not characteristics of multiple myeloma. Option 3 describes the leukemic process.

18
Q

A gastrectomy is performed on a client with gastric cancer. In the immediate postoperative period, the nurse notes bloody drainage from the nasogastric tube. The nurse should take which most appropriate action?
A/ Measure abdominal girth.
B/ Irrigate the nasogastric tube.
C/ Continue to monitor the drainage.
D/ Notify the health care provider (HCP).

A

D/ Notify the health care provider (HCP).

Following gastrectomy, drainage from the nasogastric tube is normally bloody for 24 hours postoperatively, changes to brown-tinged, and is then yellow or clear. Because bloody drainage is expected in the immediate postoperative period, the nurse should continue to monitor the drainage. The nurse does not need to notify the HCP at this time. Measuring abdominal girth is performed to detect the development of distention. Following gastrectomy, a nasogastric tube should not be irrigated unless there are specific HCP prescriptions to do so.

19
Q

A client with carcinoma of the lung develops syndrome of inappropriate antidiuretic hormone (SIADH) as a complication of the cancer. The nurse anticipates that the health care provider will request which prescriptions? SELECT ALL THAT APPLY

  1. Radiation
  2. Chemotherapy
  3. Increased fluid intake
  4. Decreased oral sodium intake
  5. Serum sodium level determination
  6. Medication that is antagonistic to antidiuretic hormone
A
  1. Radiation
  2. Chemotherapy
  3. Serum sodium level determination
  4. Medication that is antagonistic to antidiuretic hormone

Cancer is a common cause of syndrome of inappropriate antidiuretic hormone (SIADH). In SIADH, excessive amounts of water are reabsorbed by the kidney and put into the systemic circulation. The increased water causes hyponatremia (decreased serum sodium levels) and some degree of fluid retention. The syndrome is managed by treating the condition and cause and usually includes fluid restriction, increased sodium intake, and medication with a mechanism of action that is antagonistic to antidiuretic hormone. Sodium levels are monitored closely because hypernatremia can develop suddenly as a result of treatment.

20
Q
The nurse is monitoring a client for signs and symptoms related to superior vena cava syndrome. Which is an early sign of this oncological emergency?
A/ Cyanosis
B/ Arm edema
C/ Periorbital edema
D/ Mental status changes
A

C/ Periorbital edema

Superior vena cava syndrome occurs when the superior vena cava is compressed or obstructed by tumor growth. Early signs and symptoms generally occur in the morning and include edema of the face, especially around the eyes, and client complaints of tightness of a shirt or blouse collar.

21
Q

A client is diagnosed as having a bowel tumour. The nurse should monitor the client for which complications of this type of tumour? SELECT ALL THAT APPLY

  1. Flatulence
  2. Peritonitis
  3. Hemorrhage
  4. Fistula formation
  5. Bowel perforation
  6. Lactose intolerance
A
  1. Peritonitis
  2. Hemorrhage
  3. Fistula formation
  4. Bowel perforation
22
Q

The nurse is caring for a client following a mastectomy. Which nursing intervention would assist in preventing lymphedema of the affected arm?
A/ Placing cool compresses on the affected arm
B/ Elevating the affected arm on a pillow above heart level
C/ Avoiding arm exercises in the immediate postoperative period
D/ Maintaining an intravenous site below the antecubital area on the affected side

A

B/ Elevating the affected arm on a pillow above heart level

Following mastectomy, the arm should be elevated above the level of the heart. Simple arm exercises should be encouraged. No blood pressure readings, injections, intravenous lines, or blood draws should be performed on the affected arm. Cool compresses are not a suggested measure to prevent lymphedema from occurring.

23
Q
A client with squamous cell carcinoma of the larynx is receiving bleomycin intravenously. The nurse caring for the client anticipates that which diagnostic study will be prescribed?
A/ Echocardiography
B/ Electrocardiography
C/ Cervical radiography
D/ Pulmonary function studies
A

D/ Pulmonary function studies

Bleomycin is an antineoplastic medication that can cause interstitial pneumonitis, which can progress to pulmonary fibrosis. Pulmonary function studies along with hematological, hepatic, and renal function tests need to be monitored. The nurse needs to monitor lung sounds for dyspnea and crackles, which indicate pulmonary toxicity. The medication needs to be discontinued immediately if pulmonary toxicity occurs.

24
Q
A client with acute myelocytic leukemia is being treated with busulfan (Myleran, Busulfex). Which laboratory value would the nurse specifically monitor during treatment with this medication?
A/ Clotting time 
B/ Uric acid level
C/ Potassium level
D/ Blood glucose level
A

B/ Uric acid level

Busulfan (Myleran, Busulfex) can cause an increase in the uric acid level. Hyperuricemia can produce uric acid nephropathy, renal stones, and acute kidney injury.

25
Q

A clinic nurse prepares a teaching plan for a client receiving an antineoplastic medication. When implementing the plan, the nurse should make which statement to the client?
A/ “You can take aspirin (acetylsalicylic acid) as needed for headache.”
B/ “You can drink beverages containing alcohol in moderate amounts each evening.”
C/ “You need to consult with the health care provider (HCP) before receiving immunizations.”
D/ “It is fine to receive a flu vaccine at the local health fair without HCP approval because the
flu is so contagious.”

A

C/ “You need to consult with the health care provider (HCP) before receiving immunizations.”

Because antineoplastic medications lower the resistance of the body, clients must be informed not to receive immunizations without an HCP’s approval. Clients also need to avoid contact with individuals who have recently received a live virus vaccine. Clients need to avoid aspirin and aspirin-containing products to minimize the risk of bleeding, and they need to avoid alcohol to minimize the risk of toxicity and side/adverse effects.

26
Q
A client with ovarian cancer is being treated with vincristine (Vincasar). The nurse monitors the client, knowing that which manifestation indicates an adverse effect specific to this medication?
A/ Diarrhea
B/ Hair loss
C/ Chest pain
D/ Peripheral neuropathy
A

D/ Peripheral neuropathy

An adverse effect specific to vincristine is peripheral neuropathy, which occurs in almost every client. Peripheral neuropathy can be manifested as numbness and tingling in the fingers and toes. Depression of the Achilles tendon reflex may be the first clinical sign indicating peripheral neuropathy. Constipation rather than diarrhea is most likely to occur with this medication, although diarrhea may occur occasionally. Hair loss occurs with nearly all the antineoplastic medications. Chest pain is unrelated to
this medication.

Eliminate options 1 and 2 first because they are comparable or alike and are side/adverse effects associated with many of the antineoplastic agents. Note that the question asks for the adverse effect specific to this medication. Correlate peripheral neuropathy with vincristine.

27
Q
The nurse is reviewing the history and physical examination of a client who will be receiving Elspar, an antineoplastic agent. The nurse contacts the health care provider before administering the medication if which disorder is documented in the client’s history?
A/ Pancreatitis
B/ Diabetes mellitus
C/ Myocardial infarction
D/ Chronic obstructive pulmonary disease
A

A/ Pancreatitis

Asparaginase (Elspar) is contraindicated if hypersensitivity exists, in pancreatitis, or if the client has a history of pancreatitis. The medication impairs pancreatic function and pancreatic function tests should be performed before therapy begins and when a week or more has elapsed between dose administrations. The client needs to be monitored for signs of pancreatitis, which include nausea, vomiting, and abdominal pain.

28
Q
A client with metastatic breast cancer is receiving tamoxifen. The nurse specifically monitors which laboratory value while the client is taking this medication?
A/ Glucose level
B/ Calcium level
C/ Potassium level 
D/ Prothrombin time
A

B/ Calcium level

Tamoxifen may increase calcium, cholesterol, and triglyceride levels. Before the initiation of therapy, a complete blood count, platelet count, and serum calcium level should be assessed. These blood levels, along with cholesterol and triglyceride levels, should be monitored periodically during therapy. The nurse should assess for hypercalcemia while the client is taking this medication. Signs of hypercalcemia include increased urine volume, excessive thirst, nausea, vomiting, constipation, hypotonicity of muscles, and deep bone and flank pain.

29
Q
Megestrol acetate (Megace), an antineoplastic medication, is prescribed for a client with metastatic endometrial carcinoma. The nurse reviews the client’s history and should contact the health care provider if which diagnosis is documented in the client’s history?
A/ Gout
B/ Asthma
C/ Thrombophlebitis
D/ Myocardial infarction
A

C/ Thrombophlebitis

Megestrol acetate (Megace) suppresses the release of luteinizing hormone from the anterior pituitary by inhibiting pituitary function and regressing tumor size. Megestrol is used with caution if the client has a history of thrombophlebitis. Options 1, 2, and 4 are not contraindications for this medication.

Recalling that megestrol acetate is a hormonal antagonist enzyme and that an adverse effect is thrombotic disorders will direct you to the correct option.

30
Q

The nurse is monitoring the intravenous (IV) infusion of an antineoplastic medication. During the infusion, the client complains of pain at the insertion site. On inspection of the site, the nurse notes redness and swelling and that the infusion of the medication has slowed in rate. The nurse suspects extravasation and should take which actions? SELECT ALL THAT APPLY

  1. Stop the infusion.
  2. Notify the health care provider (HCP).
  3. Prepare to apply ice or heat to the site.
  4. Restart the IV at a distal part of the same vein.
  5. Prepare to administer a prescribed antidote into the site.
  6. Increase the flow rate of the solution to flush the skin and subcutaneous tissue.
A
  1. Stop the infusion.
  2. Notify the health care provider (HCP).
  3. Prepare to apply ice or heat to the site.
  4. Prepare to administer a prescribed antidote into the site.

Redness and swelling and a slowed infusion indicate signs of extravasation. If the nurse suspects extravasation during the intravenous administration of an antineoplastic medication, the infusion is stopped and the HCP is notified. Ice or heat may be prescribed for application to the site and an antidote may be prescribed to be administered into the site. Increasing the flow rate can increase damage to the tissues. Restarting an IV in the same vein can increase damage to the site and vein.

31
Q
The nurse is analyzing the laboratory results of a client with leukemia who has received a regimen of chemotherapy. Which laboratory value would the nurse specifically note as a result of the massive cell destruction that occurred from the chemotherapy?
A/ Anemia
B/ Decreased platelets
C/ Increased uric acid level 
D/ Decreased leukocyte count
A

C/ Increased uric acid level

Hyperuricemia is especially common following treatment for leukemias and lymphomas because chemotherapy results in massive cell kill. Although options 1, 2, and 4 also may be noted, an increased uric acid level is related specifically to cell destruction.

Remember that uric acid is released when cells are destroyed.

32
Q
A client with non–Hodgkin’s lymphoma is receiving daunorubicin (DaunoXome). Which finding would indicate to the nurse that the client is experiencing an adverse effect related to the medication?
A/ Fever
B/ Sores in the mouth and throat
C/ Complaints of nausea and vomiting 
D/ Crackles on auscultation of the lungs
A

D/ Crackles on auscultation of the lungs

Cardiotoxicity noted by abnormal electrocardiographic findings or cardiomyopathy manifested as heart failure (lung crackles) is an adverse effect of daunorubicin. Bone marrow depression is also an adverse effect. Fever is a frequent side effect and sores in the mouth and throat can occur occasionally. Nausea and vomiting is a frequent side effect associated with the medication that begins a few hours after administration and lasts 24 to 48 hours. Options 1, 2, and 3 are not adverse effects.

33
Q

The nurse is monitoring the laboratory results of a client receiving an antineoplastic medication by the intravenous route. The nurse plans to initiate bleeding precautions if which laboratory result is noted?
A/ A clotting time of 10 minutes
B/ An ammonia level of 20 mcg/dL
C/ A platelet count of 50,000 cells/mm3
D/ A white blood cell count of 5000 cells/mm3

A

C/ A platelet count of 50,000 cells/mm3

Bleeding precautions need to be initiated when the platelet count decreases. The normal platelet count is 150,000 to 450,000 cells/mm3. When the platelet count decreases, the client is at risk for bleeding. The normal white blood cell count is 4500 to 11,000 cells/mm3. When the white blood cell count drops, neutropenic precautions need to be implemented. The normal clotting time is 8 to 15 minutes. The normal ammonia value is 10 to 80 mcg/dL.

34
Q

What clinical finding would the nurse expect to find on a child diagnosed newly diagnosed with Acute Lymphoblastic Leukemia (ALL)?
SELECT ALL THAT APPLY

A/ Pallor
B/ Fatigue
C/ Jaundice
D/ Multiple Bruises
E/ Generalized Edema
A

A/ Pallor
B/ Fatigue
D/ Multiple Bruises

Pallor is the result of anemia associated with ALL and fatigue is the result of anemia. Multiple bruises can be attributed to thrombocytopenia associated with ALL.

Jaundice is a sign of liver damage or excessive hemolysis, which is not an early sign of leukemia.

Edema is never a sign associated with ALL.

35
Q
A client in chemotherapy asks the nurse why he's been prescribed an antibiotic also. Which tissue affected by chemotherapy should the nurse consider when formulating a response?
A/ Liver
B/ Blood
C/ Bone Marrow
D/ Lymph nodes
A

C/ Bone Marrow

Prolonged Chemotherapy may slow production of leukocytes in bone marrow; thus further suppressing the immune system. Although leukocytes are also found in the blood and lymph nodes, these are more mature cells and are more resilient to chemo.