oncology 2 Flashcards
what antifungal is not said to be effective at treating cancer induced candidiasis and what other options are available
nystatin not thought to be effective
other options miconazole topical gel or fluconazole systemically
why might a soft splint be useful for cancer patients
to try and prevent traumatic ulceration from teeth rubbing on sensitive mucosa
what virus might become reactivated in cancer patients
herpes simplex
sees painful oral ulceration of sudden onset that is aggressive and slow healing
why is increase in viscosity of saliva significant
doesnt achieve the same clearance affect so higher risk of caries, perio, candida
pilocarpine hydrochloride
product to help promote saliva secretion in patients that have retained some function
however, improvement declines after treatment stops and multiple adverse affects e.g sweating (those glands impacted too), headaches and increased urinary frequency
what makes a patient high risk of osteoradionecrosis
total radiation dose exceeded 60 Gy
dose fraction was high
person is immunodeficient
person is malnourished
are implants a possible treatment option for patients after cancer therapy
reduced success
particularly in patients who recieved radiation therapy with a total dose of 45 Gy
obturator prosthesis
denture with addition to occlude openings e.g hole into maxillary sinus
what should be done if a patients blood count shows there neutrophil levels are below one
give antibiotic prophylaxis prior to invasive dental treatment
what does the child pugh score tell us
degree of liver cirrhosis
what does the challacombe score tell us
grades clinical oral dryness from 1-10
what are key teeth to try and retain and why
anteriors (aesthetics)
canines (strong, prosthesis support)
occluding pairs (function and quality of life)
what are patients taking monoclonal antibodies more susceptible to
infection
what does the GFR measure
(glomerular filtration rate)
measures kidney function
drugs ending -umab
human monoclonal antibody drugs
a type of biologic drug
all biologic drug side effects are different but name 3 potential ones
increased bleeding risk
decreased healing capacity
increased infection risk
what is the minimum platelet count for invasive dental treatment
in general practice 100
in hospital 50
why might articaine be considered for patients with severe liver problems
articaine is also metabolised in plasma rather than solely in the liver like other local anaesthetics
drugs ending -olol
beta blockers
decrease HR
why cant invasive dental treatment be done on patients who have undergone dialysis on the same day
patients get put on blood thinners during dialysis to prevent clotting
ideally at least a day should be waited before invasive dental treatment carried out to reduce bleeding tendency
