Oncology Flashcards

1
Q

name 3 instances a refferal to oral medicine would be appropriate

A
  • persistent unexplained head or neck lumps for > 3 weeks
  • ulceration or unexplained swelling of oral mucosa for > 3 weeks
  • all red or mixed red and white patches of oral mucosa for > 3 weeks
  • dysphagia or odynophagia for > 3 weeks
  • stridor (high pitched wheeze when breathing)
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2
Q

what should you provide for patients about to start cancer treatment (dental pre assessment) (advice)

A

smoking cessation
alcohol advice
detailed oral hygiene instruction
consider chlorhexidine mouthwash when in too much pain to brush
advise against wearing denture during treatment as mouth will become very tender and sore
duraphat toothpaste

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3
Q

what treatment should you undertake on patients about to start cancer treatment (dental pre assessment) (treatment)

A
  • PMPR to stabilise any periodontal conditions
  • definitively restore any areas of caries
    remove any areas risking trauma e.g sharp edges of teeth or restorations
  • take impressions so that soft splints and fluoride trays can be provided down the line
  • extract any teeth with dubious prognossis
  • remove any fixed orthodontic appliances
  • remove any sources of infection
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4
Q

what is the minimum number of days that should be left before a patient begins cancer treatment if you are performing a tooth extraction

A

no less than 10 days

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5
Q

what cancer treatment is oral mucositis most commonly seen as a side effect of

A

chemotherapy

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6
Q

if patient suffers oral mucositis when does it begin and last till

A

begins 1-2 weeks after treatment begins and can last up until 6 weeks post treatment

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7
Q

oral mucositis

A

painful inflammation and ulceration of the oral mucosa experienced by patients undergoing cancer treatment e.g chemo or radio therapy
in severe cases , pain so bed patients require hospitalisation and tube fed.

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8
Q

does good OH help mucositis

A

will not prevent symptoms but may help it resolve faster once cancer treatment complete

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9
Q

name 3 management options for oral mucositis

A
  • caphosol - mouthrinse that mimics saliva and aims to relieve some pain and discomfort
  • Gelclair - viscous gel that forms a protective layer over the oral mucosa aiming to offer some pain relief
  • chlorhexidine mouthwash
  • cryotherapy
  • strong analgesics for pain control e.g opiods (doctor will prescribe)
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10
Q

mucositis grading scale (WHO)

A

grade 0 = none
1 - oral soreness and erythema
2 - erythema, ulcers but solid diet tolerated
3 - ulcers, liquid diet only
4 - oral alimentation impossible

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11
Q

what are your two main priorities for a patient prior to them starting chemotherapy

A

remove any current or potential sources of infection
institute prevention - detailed OHI , PMPR, fluoride varnish

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12
Q

what is used to ensure radiotherapy is only delivered to desired areas

A

porous mask that immobilises the patients head - individually specific to each patient

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13
Q

what type of radiotherapy can spare the salivary glands

A

intensity modulated radiotherapy (IMRT)

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14
Q

chemotherapy affects on the body

A

impaired immune system - reduced white cells
haematological effects resulting in coagulation defects

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15
Q

side effects of chemotherapy

A

alopecia
nausea
vomiting
anorexia
bone marrow suppression
reproductive function damage
mucositis

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16
Q

why might trismus occur in cancer patients

A

fibrosis of muscles of mastication
tumour growth
infection
surgery

17
Q

above what dose of radiotherapy is osteoradionecrosis at greatest risk

A

doses over 60Gy

18
Q

how is the dose of radiotherapy calculated

A

radiotherapy usually given in small amounts (fractions) on a daily basis
(usually 5 days on 2 days off per week)
total dose is a cumulative total of all radiation given

19
Q

hypogeusia

A

loss of taste
possible side effect of radiation to taste buds

20
Q

how does osteoradionecrosis occur

A

exposed vascular bone
radiation therapy induces obliterating endartritis (inflammation of inner lining of artery leading to occlusion of lumen)
this leads to progressive fibrosis and capillary loss leaving bone susceptible to avascular necrosis.
This predisposes the bone to ORN that often results from dental extractions carried out post radiotherapy