oncogenes and tumor suppressor genes Flashcards by Josh Spiegel

Q

bcr-abl

A

CML, ALL

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Q

bcl-2

A

follicular and undifferentiated lymphomas

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Q

BRAF

A

melanoma

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Q

c-kit

A

GIST

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Q

c-myc

A

burkitt lymphoma

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Q

HER2/neu

A

breast ovarian

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Q

L-myc

A

lung tumor

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Q

N-myc

A

neuroblastoma

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Q

RAS

A

colon cancer, lung and pancreatic cancer

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Q

ret

A

MEN2A & 2B

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Q

APC

A

colorectal cancer

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Q

BRCA1 and 2

A

breast and ovarian

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Q

SMAD4

A

pancreatic cancer

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Q

DCC

A

colon cancer

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Q

MEN1

A

MEN 1

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Q

NF1

A

Neurofibromatosis 1

Q

NF2

A

neurofibromatosis 2

Q

p16

A

melanoma

Q

p53

A

li fraumeni syndrome

Q

PTEN

A

breast cancer, prostate cancer, endometrial cancer

Q

Rb

A

retinoblastoma, osteosarcoma

Q

TSC1

A

tuberous sclerosis

Q

TSC2

A

tuberous sclerosis

Q

VHL

A

von hippel lindau dz

Q

WT1 &2

A

wilms tumor