neurotransmitter changes in neuro dz Flashcards
1
Q
NE
A
inc in anxiety/mania
dec in depression
2
Q
what is the location of NE synth
A
Locus ceruleus
3
Q
DA
A
inc in huntingtons
inc in schizophrenia
Dec in parkinsons dz
Dec in depression
4
Q
where is DA synthesized
A
Ventral tegmentum and SNc
5
Q
what is the rewards center
A
nucleus accumbens
6
Q
5-HT
A
inc in parkinsons
dec in anxiety
dec in depression
7
Q
Where is 5-HT synthesized
A
Raphe nucleus
8
Q
ACh
A
inc in parkinsons
dec in alzheimers
dec in huntingtons
9
Q
where is ACh synthesized
A
basal nucleus of meynert
10
Q
GABA
A
dec in anxiety
dec in huntingtons
11
Q
where is GABA synthesized
A
nucleus accumbens
12
Q
what is needed for GABA synth
A
vit B6
13
Q
What NT changes are seen in Anxiety
A
inc NE
dec 5-HT
dec GABA
14
Q
What NT changes are seen in depression
A
Dec NE
dec DA
dec 5-HT
15
Q
What NT changes are seen in huntingtons dz
A
inc DA
dec ACh
dec GABA
