Antifungals Flashcards by Josh Spiegel | Brainscape

Q

interferes w/ microtubule fxn

A

grizeofulvin

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Q

swish and swallow for oral candidiasis

A

nystatin

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Q

cell wall synth inn used for invasive aspergillosis

A

caspofungin

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Q

binds ergosterol –> membrane pores

A

amphotericin B and nystatin

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Q

Inh ergosterol synthesis

A

azoles, terbinefine

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Q

MC tx for onychomycosis

A

terbinafine and itraconazole

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Q

arrythmias and nephrotoxidicy

A

amphotericin B

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Q

deposits in keratin containing tissues

A

griseofulvin

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Q

inhibits hormone synthesis and CYP450

A

azoles

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Q

liver dysfxn

A

azoles and grizeofulvin

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Q

teratogenic

A

grizeofulvin

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Q

used for cryptococcal meningitis in aids pts

A

IV amphotericin B and flucytosine

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Q

converted to fluorouracil and inhibits DNA synth

A

flucytosine

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Q

Drugs of choice for sporotrichosis

A

itraconazole

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