Oncogenes Flashcards

1
Q

CML?

A

abl

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2
Q

Burkitt’s lymphoma?

A

c-myc

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3
Q

Follicular and undifferentiated lymphomas?

A

bcl-2

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4
Q

Breast, ovarian, and gastric carcinomas?

A

HER2/neu (c-erbB2)

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5
Q

Colon carcinoma?

A

ras

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6
Q

Lung tumor?

A

L-myc

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7
Q

Neuroblastoma?

A

N-myc

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8
Q

MEN 2A and 2B?

A

ret

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9
Q

GI stromal tumor (GIST)?

A

c-kit

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10
Q

abl?

A

Tyrosine kinase

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11
Q

c-myc?

A

Txc factor

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12
Q

bcl-2?

A

Inhibits apoptosis

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13
Q

HER2/neu (c-erbB2)?

A

Tyrosine kinase

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14
Q

ras?

A

GTPase

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15
Q

L-myc?

A

Txc factor

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16
Q

N-myc?

A

Txc factor

17
Q

ret?

A

Tyrosine kinase

18
Q

c-kit?

A

Cytokine receptor

20
Q

PDGFB?

A

Astrocytoma

20
Q

CCND1 (cyclin D1)?

A

Mantle cell lymphoma