Chemical Carcinogens Flashcards

1
Q

Aflatoxins (Aspergillus)?

A

HCC

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2
Q

Vinyl chloride?

A

Angiosarcoma of liver

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3
Q

Carbon tetrachloride?

A

Centrilobular necrosis, fatty change

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4
Q

Nitrosamines (smoked foods)?

A

Gastric cancer

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5
Q

Cigarette smoke?

A

SCC of larynx and lung, small cell of lung, RCC, transitional cell carcinoma, pancreatic adenocarcinoma

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6
Q

Asbestos?

A

Bronchogenic carcinoma > mesothelioma

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7
Q

Arsenic?

A

SCC of skin, angiosarcoma of liver

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8
Q

Naphthalene (aniline) dyes?

A

Transitional cell carcinoma

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9
Q

Alkylating agents?

A

Leukemia

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10
Q

Alcohol?

A

SCC of oropharynx and upper esophagus, pancreatic carcinoma, and HCC

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11
Q

Nickel, chromium, beryllium, or silica?

A

Lung carcinoma (occupational exposure)

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12
Q

Most common carcinogen worldwide?

A

Cigarette smoke–polycyclic hydrocarbon especially

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13
Q

Key carcinogen causing bladder carcinoma?

A

Cigarette smoke

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