Disease Conditions Associated with Neoplasms

Question 1

Down syndrome?

Answer 1

ALL, AML

Question 2

Xeroderma pigmentosum?

Answer 2

All skin cancer types

Question 3

Albinism?

Answer 3

All skin cancer types

Question 4

Chronic atrophic gastritis?

Answer 4

Gastric adenocarcinoma

Question 5

Tuberous sclerosis?

Answer 5

Giant cell astrocytoma, renal angiomyolipoma, cardiac rhabdomyoma

Question 6

Pernicious anemia?

Answer 6

Gastric adenocarcioma

Question 7

Actinic keratosis?

Answer 7

SCC of skin

Question 8

Barrett’s?

Answer 8

Esophageal adenocarcinoma

Question 9

Plummer-Vinson?

Answer 9

SCC of esophagus

Question 10

Postsurgical gastric remnants?

Answer 10

Gastric adenocarcinoma

Question 11

Cirrhosis (alcoholic, hep B or C)?

Answer 11

HCC

Question 12

UC?

Answer 12

Colonic adenocarcinoma

Question 13

Paget’s disease of bone?

Answer 13

Secondary osteosarcoma and fibrosarcoma

Question 14

Immunodeficiency states?

Answer 14

Malignant lymphomas

Question 15

AIDS?

Answer 15

Aggressive malignant lymphomas (non-Hodgkin’s) and Kaposi’s sarcoma

Question 16

Autoimmune diseases (e.g. Hashimoto’s, MG)?

Answer 16

Lymphoma

Question 17

Acanthosis nigricans?

Answer 17

Visceral malignancy (stomach, lung, uterus)

Question 18

Dysplastic nevus?

Answer 18

Malignant melanoma

Question 19

Ionizing radiation (nuclear reactor accidents and radiotherapy)?

Answer 19

AML, CML, and papillary thyroid carcinoma

Question 20

Nonionizing radiation (UVB sunlight is most common source)?

Answer 20

All types of skin cancer (results in formation of pyrimidine dimers in DNA, which are normally excised by restriction endonuclease)