Disease Conditions Associated with Neoplasms Flashcards by Ryan Bray

Down syndrome?

ALL, AML

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Xeroderma pigmentosum?

All skin cancer types

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Albinism?

All skin cancer types

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Chronic atrophic gastritis?

Gastric adenocarcinoma

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Tuberous sclerosis?

Giant cell astrocytoma, renal angiomyolipoma, cardiac rhabdomyoma

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Pernicious anemia?

Gastric adenocarcioma

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Actinic keratosis?

SCC of skin

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Barrett’s?

Esophageal adenocarcinoma

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Plummer-Vinson?

SCC of esophagus

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Postsurgical gastric remnants?

Gastric adenocarcinoma

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Cirrhosis (alcoholic, hep B or C)?

HCC

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UC?

Colonic adenocarcinoma

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Paget’s disease of bone?

Secondary osteosarcoma and fibrosarcoma

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Immunodeficiency states?

Malignant lymphomas

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AIDS?

Aggressive malignant lymphomas (non-Hodgkin’s) and Kaposi’s sarcoma

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Autoimmune diseases (e.g. Hashimoto’s, MG)?

Lymphoma

Acanthosis nigricans?

Visceral malignancy (stomach, lung, uterus)

Dysplastic nevus?

Malignant melanoma

Ionizing radiation (nuclear reactor accidents and radiotherapy)?

AML, CML, and papillary thyroid carcinoma

Nonionizing radiation (UVB sunlight is most common source)?

All types of skin cancer (results in formation of pyrimidine dimers in DNA, which are normally excised by restriction endonuclease)