Oncogenes Flashcards
1
Q
ALK
A
Receptor Tyrosine Kinase
Lung Adenocarcinoma
2
Q
BCR-ABL
A
Tyrosine Kinase
CML, ALL
3
Q
BCL-2
A
Anti-apoptotic Molecule
Follicular and Diffuse Large B Cell Lymphomas
4
Q
BRAF
A
Serine/Threonine Kinase
Melanoma and non-Hodgkin Lymphoma
5
Q
c-KIT
A
Cytokine Receptor
Gastrointestinal Stromal Tumor (Tumor)
6
Q
c-MYC
A
Transcription Factor
Burkitt Lymphoma
7
Q
HER2/NEU
A
Tyrosine Kinase
Breast and Gastric Cancer
8
Q
JAK2
A
Tyrosine Kinase
Chronic Myeloproliferative Disorders
9
Q
KRAS
A
GTPase
Colon, Lung, and Pancreatic Cancer
10
Q
MYCL1
A
Transcription Factor
Lung Tumors
11
Q
MYCN
A
Transcription Factor
Neuroblastoma
12
Q
RET
A
Tyrosine Kinase
MEN2A, MEN2B, and Medullary Thyroid Cancer