Oncogenes Flashcards

1
Q

ALK

A

Receptor Tyrosine Kinase

Lung Adenocarcinoma

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2
Q

BCR-ABL

A

Tyrosine Kinase

CML, ALL

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3
Q

BCL-2

A

Anti-apoptotic Molecule

Follicular and Diffuse Large B Cell Lymphomas

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4
Q

BRAF

A

Serine/Threonine Kinase

Melanoma and non-Hodgkin Lymphoma

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5
Q

c-KIT

A

Cytokine Receptor

Gastrointestinal Stromal Tumor (Tumor)

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6
Q

c-MYC

A

Transcription Factor

Burkitt Lymphoma

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7
Q

HER2/NEU

A

Tyrosine Kinase

Breast and Gastric Cancer

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8
Q

JAK2

A

Tyrosine Kinase

Chronic Myeloproliferative Disorders

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9
Q

KRAS

A

GTPase

Colon, Lung, and Pancreatic Cancer

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10
Q

MYCL1

A

Transcription Factor

Lung Tumors

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11
Q

MYCN

A

Transcription Factor

Neuroblastoma

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12
Q

RET

A

Tyrosine Kinase

MEN2A, MEN2B, and Medullary Thyroid Cancer

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