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Systemic Pathology 2018 > Old Exam Questions - Castleman > Flashcards

Old Exam Questions - Castleman Flashcards

1
Q

The most common anatomic form of lymphoma in dogs is ____

A

Mutlicentric

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2
Q

The most common anatomic form of lymphoma in cats is ____

A

Alimentary

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3
Q

Right atrial lymphoma is most commonly found in ____

A

Cattle

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4
Q

Viral agents have been associated with lymphoma in ____

A

Cats, dogs and cattle

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5
Q

All of the following resulting decreased size of the thymus, EXCEPT:

a. parvovirus
b. lymphoma
c. corticosteroids
d. canine distemper
e. a and d

A

b. lymphoma

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6
Q

A uniformly enlarged dog spleen that bleeds on cut surface is most likely:

a. hemangiosarcoma
b. hemangioma
c. lymphoma
d. congestion
e. nodular hyperplasia

A

d. congestion

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7
Q

An irregular dark red nodule in a spleen that bleeds on cut surface could be all of the following, EXCEPT:

a. hemangiosarcoma
b. hemangioma
c. granulomatous splenitis
d. hematoma
e. nodular hyperplasia

A

c. granulomatous splenitis

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8
Q

B-cells are located in which areas of lymph nodes?

a. follicular areas
b. parafollicular areas
c. medullary cords
d. a and b
e. a and c

A

e. a and c

- follicular areas and medullary cords

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9
Q

Vesicular oral lesions can be induced by all of the following, EXCEPT:

a. foot and mouth disease virus
b. thermal injury
c. vesicular stomatitis virus
d. swine vesicular disease virus
e. bovine papular stomatitis virus

A

e. bovine papular stomatitis virus

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10
Q

Oral ulcerative lesions can be induced by:

a. chronic uremia
b. calicivirus
c. bovine viral diarrhea virus
d. foot and mouth disease virus
e. all of the above

A

e. all of the above

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11
Q

Morphologic diagnosis: chronic focal necrotizing stomatitis
The most likely cause of is trauma and infection by:
a. candida albicans
b. bovine papular stomatitis virus
c. fusobacterium necrophorum
d. foot and mouth disease virus
e. trueperella pyogenes

A

c. fusobacterium necrophorum

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12
Q

Which of the following oral neoplasms in dogs has the least probability of invasion and/or metastasis?

a. melanoma
b. periodontal fibromatous epulis
c. acanthomatous ameloblastoma
d. fibrosarcoma
e. leiomyosarcoma

A

b. periodontal fibromatous epulis

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13
Q

Which of the following oral neoplasms has the greatest probability of metastasis?

a. tonsillar squamous cell carcinoma
b. periodontal fibromatous epulis
c. acanthomatous ameloblastoma
d. squamous papilloma
e. leiomyoma

A

a. tonsillar squamous cell carcinoma

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14
Q

Which of the following infectious agents induces villous atrophy?

a. rotavirus
b. coronavirus
c. cryptosporidia sp.
d. parvovirus
e. all of the above

A

e. all of the above

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15
Q

Which of the following infectious agents induces necrosis of crypt epithelial cells?

a. rotavirus
b. coronavirus
c. cryptosporidia sp.
d. parvovirus

A

d. parvovirus

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16
Q

In dogs with villous atrophy and diarrhea due to canine parvovirus type 2, what other gross findings is most likely present?

a. ulcerative stomatitis
b. lymph node hyperplasia with abscesses
c. necrotizing rhinitis
d. thymic atrophy
e. ileocecal intussusception

A

d. thymic atrophy

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17
Q

Which of the following infectious agents most commonly induces fibrinonecrotic enterocolitis?

a. rotavirus
b. salmonella sp.
c. cryptosporidia sp.
d. mycobacteria sp.
e. lawsonia intracellularis

A

b. salmonella sp.

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18
Q

Which of the following infectious most commonly produces proliferative enteritis?

a. rotavirus
b. salmonella sp.
c. cryptosporidia sp.
d. mycobacteria sp.
e. lawsonia intracellularis

A

e. lawsonia intracellularis

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19
Q

Granulomatous enteritis is most commonly associated with which of the following pathogens?

a. rotavirus
b. salmonella sp.
c. cryptosporidia sp.
d. mycobacteria sp.
e. lawsonia intracellularis

A

d. mycobacteria sp.

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20
Q

Which of the following is the most common intestinal neoplasm in cats?

a. lymphoma
b. adenocarcinoma
c. leiomyoma/GIST
d. carcinoid

A

a. lymphoma

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21
Q

The most common site for intestinal adenocarcinoma in cats?

a. small intestine
b. large intestine

A

a. small intestine

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22
Q

Which of the following is NOT a stem cell for epithelial repair?

a. mucous cells
b. ciliated cells
c. non-ciliated cells

A

b. ciliated cells

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23
Q

Which of the following serves as stem cells for epithelial repair in the inter alveolar septum?

a. type 1 alveolar epithelial cells
b. type 2 alveolar epithelial cells
c. mucous cell

A

b. type 2 alveolar epithelial cells

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24
Q

The most common cause of bronchiectasis is?

A

chronic bacterial infection

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25
Q

Which of the following processes is reversible?

a. bronchiectasis
b. bronchiolitis obliterans
c. atelectasis
d. alveolar emphysema

A

c. atelectasis

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26
Q

If the distribution of pneumonia is cranioventral, what is the most likely morphologic diagnosis?

a. aspiration pneumonia
b. fungal pneumonia
c. viral pneumonia
d. bronchopneumonia
e. interstitial pneumonia

A

d. bronchopneumonia

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27
Q

If it is bronchopneumonia, the most likely cause(s) is/are:

a. bacteria
b. virus
c. aspiration
d. a and b
e. a and c

A

e. a and c

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28
Q

If the pneumonia is diffuse, the LEAST likely cause is:

a. virus
b. protozoa
c. toxins
d. aspiration
e. bacterial septicemia

A

d. aspiration

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29
Q

Which of the following pulmonary injuries is most likely to induce the most severe irreversible lung and pleural damage?

a. viral infection
b. bacterial infection
c. dietary pneumotoxins

A

b. bacterial infection

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30
Q

What mechanism accounts for some respiratory viruses being able to induce chronic pneumonia and diffuse interstitial pneumonia?

a. they replicate in type 1 epithelial cells
b. they replicate in type 2 epithelial cells
c. they evade or suppress immunological defense mechanisms

A

c. they evade or suppress immunological defense mechanisms

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31
Q

Acute respiratory viral infections often induce pulmonary lesions including:

a. bronchitis
b. bronchiolitis
c. patchy interstitial pneumonia
d. diffuse interstitial pneumonia
e. a, b and c

A

e. a, b and c

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32
Q

The most common form of pulmonary neoplasia is:

a. adenoma
b. adenocarcinoma
c. fibrosarcoma
d. leiomyoma
e. metastatic

A

e. metastatic

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33
Q

Which of the following contain toxins activated by pulmonary cytochrome P450 monoxygenase to induce interstitial pneumonia in cattle and/or horses?

a. moldy sweet potatoes
b. mold damaged corn
c. purple mint (perilla mint)
d. a, b and c
e. a and c

A

e. a and c

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34
Q

Which of the following viruses induce tracheitis, bronchitis, bronchiolitis and interstitial pneumonia in dogs?

a. canine distemper virus
b. H3N8 CIV
c. H3N2 CIV
d. canine adenovirus type 2
e. all of the above

A

e. all of the above

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35
Q

Which of the following viruses causes systemic lymphoid atrophy?

a. canine parvovirus type 2
b. EHV-1
c. canine distemper virus
d. feline panleukopenia virus
e. all of the above

A

e. all of the above

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36
Q

Multicentric lymphoma in the dog most commonly infiltrates what organs/tissue?

a. peripheral lymph nodes, liver, and gastrointestinal tract
b. peripheral and visceral lymph nodes, spleen, liver
c. peripheral lymph nodes, kidney, liver and spleen
d. visceral lymph nodes, kidney, liver and spleen
c. visceral lymph nodes, spleen, liver and gastrointestinal tract

A

c. peripheral lymph nodes, kidney, liver and spleen

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37
Q

Bone marrow involvement in lymphoma in cattle is most commonly associated with which of the following forms?

a. multicentric
b. cutaneous
c. thymic
d. calf
e. alimentary

A

c. thymic

I don’t know whether this would be calf or thymic or both…I put thymic since thymic > calf on occurrence list

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38
Q

Thymoma is a neoplasm of?

a. thymic epithelial cells
b. thymic lymphocytes
c. thymic smooth muscle cells
d. thymic macrophages
e. a and b

A

a. thymic epithelial cells

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39
Q

Which of the following are common sites for lymphoma in adult cattle with multicentric lymphoma?

a. lymph nodes
b. abomasum
c. brain
d. a, b
e. a, b, c

A

d. a, b

seen in lymph nodes, right atrium, abomasum, kidneys, uterus and spinal epidural fat

40
Q

All of the following commonly present with bloody nodular splenic masses in dogs EXCEPT?

a. Hematoma
b. Hemangioma
c. Hemangiosarcoma
d. Lymphoma
e. Splenic infarct

A

d. Lymphoma

41
Q

Which of the following diseases or infections can result in generalized lymphadenomegaly?

a. Multicentric lymphoma
b. Malignant catarrhal fever
c. Canine parvovirus 2 infection
d. A, B
e. A, B, C

A

d. A, B

Parvo = atrophy

42
Q

Retrovirus infection has been identified as a cause of lymphoma in?

a. Dogs
b. Cats
c. Cattle
d. A, B, C
e. B, C

A

e. B, C

43
Q

The most common cardiac site for lymphoma in cattle is?

a. Right atrium
b. Right ventricle
c. Left atrium
d. Left ventricle
e. Aortic valve

A

a. Right atrium

44
Q

Which of the following terms are used synonymously with lymphoma in veterinary medicine?

a. Lymphoproliferative disease
b. Lymphosarcoma
c. Myeloma
d. A, B
e. A, B, C

A

d. A, B

45
Q

All of the following often result in generalized (diffuse) splenomegaly EXCEPT?

a. Histoplasmosis
b. Septicemic salmonellosis
c. Lymphoma
d. Hematoma
e. Congestion

A

d. Hematoma

46
Q

Viruses that induce thymic atrophy include which of the following?

a. Canine distemper virus
b. Canine parvovirus 2
c. Canine coronavirus
d. A and B
e. A, B and C

A

d. A and B

47
Q

If you identified the illustrated splenic changes (bloody nodule) during abdominal surgery in a dog, what would be the most important tissue to evaluate for possible metastases or primary sites of tumor?

a. Right atrium
b. Adrenal
c. Digits
d. Stomach
e. Kidneys

A

If it’s a bloody looking nodule (hemangiosarcoma), then look at the right atrium

48
Q

Bronchiectasis is most often associated with which of the following?

a. Viral infection
b. Fungal infection
c. Bacterial infection
d. Alveolar emphysema
e. Interstitial emphysema

A

c. Bacterial infection

49
Q

The lung lesions from a foal that died suddenly is most consistent with which of the following causes/pathogenesis?

a. Aspiration
b. Descending bacterial infection
c. Toxoplasmosis
d. Pulmonary arterial thrombosis
e. Bacterial septicemia

A

e. Bacterial septicemia

sorry no picture lol

50
Q

All of the following forms of lung lesions are reversible EXCEPT?

a. Bronchiectasis
b. Alveolar edema
c. Interstitial emphysema
d. Compressive atelectasis
e. A and C

A

a. Bronchiectasis

Others - alveolar emphysema, bronchiolitis obliterans

51
Q

All of the following are common features of acute bacterial bronchopneumonia in cattle EXCEPT?

a. Abundant alveolar exudates that includes neutrophils
b. Diffuse pulmonary distribution
c. Increase firmness of affected lung
d. Concurrent fibrinous pleuritis
e. Bronchiolar oriented inflammatory infiltrate in alveoli

A

b. Diffuse pulmonary distribution

52
Q

What would be the best gross pathologic criterion for determining that pulmonary changes represent pneumonia, rather than simple atelectasis?

a. Redness of lung
b. Warmth of lung
c. Firmness of lung
d. Fibrin on the pleural surface
e. Exudate in bronchi on cut section

A

c. Firmness of lung

53
Q

Which of the following respiratory diseases can commonly be associated with diffuse interstitial pneumonia?

a. Moldy sweet potato toxicity in cattle
b. Canine distemper virus infection in dogs
c. Ovine progressive pneumonia
d. Pneumocystis carinii infection in foals
e. All of the above

A

e. All of the above

54
Q

All of the following function as stem cells for epithelial repair in the lung EXCEPT?

a. Ciliated cells
b. Mucous cells
c. Nonciliated bronchiolar epithelial cells
d. Basal cells
e. Type 2 alveolar epithelial cells

A

a. Ciliated cells

55
Q

All of the following diseases result in restrictive respiratory disease EXCEPT?

a. Interstitial pneumonia
b. Fibrinous pneumonia
c. Alveolar emphysema
d. Pulmonary fibrosis
e. Alveolar edema

A

c. Alveolar emphysema

Causes decrease in effective elastic tissue and increased compliance

56
Q

Gastric ulceration of the squamous portion of the mucosa with fatal hemorrhage occurs commonly in?

a. Horses
b. Pigs
c. Dogs
d. Cattle
e. Cats

A

b. Pigs

57
Q

The oral/pharyngeal neoplasm in dogs most likely to metastasize is?

a. Gingival melanoma
b. Fibrosarcoma on the hard palate
c. Tonsillar squamous cell carcinoma
d. Gingival acanthomatous ameloblastoma
e. Melanoma on the lip

A

c. Tonsillar squamous cell carcinoma

58
Q

Stem cells for epithelial renewal in the small intestine are present in?

a. Villus tips
b. Crypts
c. A and B

A

b. Crypts

59
Q

Which of the following oral neoplasms in the dog metastasize?

a. Melanoma
b. Fibromatous epulis
c. Squamous cell carcinoma
d. Acanthomatous ameloblastoma
e. A and C

A

e. A and C

60
Q

The pulmonary airways with the lower amount of total cross sectional area in the lung and the greater air velocity during respiration that allow ausculation of lung sounds are?

a. Bronchi
b. Bronchioles

A

a. Bronchi

61
Q

Ulceration/erosion of the lingual mucosa in cats can be due all of the following EXCEPT?

a. Calicivirus
b. Herpesvirus
c. Chronic uremia
d. Fibromatous epulis
e. Squamous cell carcinoma

A

d. Fibromatous epulis

62
Q

All of the following forms of lung lesions are irreversible EXCEPT?

a. Bronchiectasis
b. Alveolar edema
c. Alveolar emphysema
d. Compressive atelectasis
e. B and D

A

e. B and D

63
Q

Which of the following are common sites for lymphoma in adult cattle with multicentric lymphoma?

a. Lymph nodes
b. Abomasum
c. Uterus
d. Right atrium
e. A, B, C and D

A

e. A, B, C and D

64
Q

Which of the following responses is a (are) useful gross indicator(s) of chronicity in bovine bronchopneumonia

a. tracheobronchial lymphadenomegaly
b. bronchiectasis
c. pleural fibrosis
d. A and B
e. A, B and C

A

e. A, B and C

65
Q

Which of the following is an obstructive respiratory disease?

a. Pneumothorax
b. Bronchiolitis
c. Intersitial emphysema
d. Alveolar emphysema
a. B and D

A

a. B and D

66
Q

All of the following are lesions found in canine distemper EXCEPT?

a. Intracytoplasmic inclusions in bronchial epithelial cells
b. Multifocal, randomly distributed pin-point white foci in the lung grossly
c. Intracytoplasmic inclusion in urinary bladder epithelial cells
d. Multifocal demyelinating encephalitis
e. Intracytoplasmic inclusions in bronchial gland epithelial cells

A

b. Multifocal, randomly distributed pin-point white foci in the lung grossly

67
Q

Which of the following respiratory diseases can commonly be associated with diffuse interstitial pneumonia?

a. Pulmonary toxoplasmosis in cats
b. Fusobacterium necrophorum in cattle
c. Ovine progressive pneumonia
d. A, B and C
e. A and C

A

e. A and C

68
Q

Which of the following oral neoplasms in the dog does not metastasize?

a. Melanoma
b. Fibromatous epulis
c. Squamous cell carcinoma
d. Acanthomatous ameloblastoma
e. B and D

A

e. B and D

69
Q

Which of the following is the most common gastric neoplasm in the horse?

a. Lymphoma
b. Mast cell tumor
c. Adenocarcinoma
d. Leiomyosarcoma
e. Squamous cell carcinoma

A

e. Squamous cell carcinoma

70
Q

This lung from a dog with necrotizing pancreatitis that was firm in dark red areas is most consistent with which of the following conditions?

a. pulmonary thrombosis and infarction
b. bacterial septicemia
c. aspiration pneumonia
d. compressive atelectasis e. postobstructive atelectasis

A

c. aspiration pneumonia

71
Q

Viruses that induce thymic atrophy include which of the following?

a. Canine distemper virus b. Canine parvovirus 2
c. Feline panleukopenia virus
d. A and B
e. A, B and C

A

e. A, B and C

72
Q

What is the cause of most bronchopneumonias?

a. Aspiration of foreign material
b. Bacterial infection
c. Fungal infection
d. Dietary toxin
e. A and/or B

A

e. A and/or B

73
Q

The most appropriate morphologic diagnosis for the spongy, soft lungs from this cat with cardiomyopathy and hydrothorax is?

a. locally-extensive alveolar emphysema
b. locally-extensive interstitial emphysema
c. locally-extensive post-obstructive atelectasis
d. locally-extensive compressive atelectasis
e. locally-extensive bronchopneumonia

A

d. locally-extensive compressive atelectasis

74
Q

All of the following forms of lung lesions are irreversible EXCEPT:

a. Bronchiectasis
b. Alveolar edema
c. Alveolar emphysema
d. Compressive atelectasis
d. b and d

A

d. b and d

75
Q

Bronchopneumonia is characterized by all of the following EXCEPT:
A. Airway-oriented inflammatory exudate
B. Abundant inflammatory exudate in alveolar spaces
C. Features of both restrictive and obstructive respiratory disease
D. Can be induced by aspiration of foreign material
E. Predominantly caudodorsal distribution in lungs

A

E. Predominantly caudodorsal distribution in lungs

76
Q

Which of the following is a morphologic diagnosis?
A. Hemangiosarcoma of the spleen
B. Acute suppurative bronchitits
C. Multicentric lymphoma
D. Chronic locally-extensive fibrinous bronchopneumonia
E. All of the above

A

E. All of the above

77
Q

Which of the following viruses in cattle commonly induce syncytial bronchiolar epithelial cells following respiratory infection?

a. Adenovirus
b. Bovine herpesvirus type 1
c. Rhinovirus
d. Parainfluenza virus type 3
e. A and C

A

d. Parainfluenza virus type 3

78
Q

All of the following are common features of acute bacterial bronchopneumonia in cattle EXCEPT:

a. Abundant alveolar exudates that includes neutrophils
b. Diffuse pulmonary distribution
c. Increase firmness of affected lung
d. Concurrent fibrinous pleuritis
e. Bronchiolar oriented inflammatory infiltrate in alveoli

A

b. Diffuse pulmonary distribution

79
Q

Which of the following respiratory disease can commonly be associated with diffuse interstitial pneumonia?

a. pulmonary toxoplasmosis in cats
b. canine distemper virus in dogs
c. ovine progressive pneumonia
d. pneumocystitis carinii infection
e. all of the above

A

e. all of the above

80
Q 
The pathophysiologic mechanism that accounts for hypoxemia in horses with chronic bronchiolitis is:
A. Ventilation/perfusion inequality 
B. Increased resistance
C. Decreased resistance
D. Increased compliance
E. Decreased compliance.
A

A. Ventilation/perfusion inequality

81
Q 
Splenic hemangiosarcoma in the dog commonly is associated with metastasis/involvement in all of the following other tissues EXCEPT?
A. Right atrium of the heart B. Liver
C. Lung
D. Bladder
E. A and D
A

D. Bladder

82
Q 
Which of the following diseases or infections can result in generalized lymphadenomegaly?
A. Multicentric lymphoma
B. Bovine leukemia virus infection
C. Malignant catarrhal fever
D. A, B
E. A, B, C
A

E. A, B, C

83
Q

All of the following are morphologic diagnoses EXCEPT:
A. Lymphoma of lymph nodes
B. Chronic locally-extensive fibrinopurulent bronchopneumonia
C. Acute multifocal suppurative splenitis
D. Hemangiosarcoma of spleen
E. Herpesvirus pneumonia

A

E. Herpesvirus pneumonia

84
Q

All of the following viruses cause systemic lymphoid atrophy EXCEPT:
A. Canine parvovirus type 2
B. Canine adenovirus type 2
C. EHV-1 (Equine herpes virus 1) D. Canine distemper virus
E. Feline panleukopenia virus

A

B. Canine adenovirus type 2

85
Q 
Which of the following diseases or processes usually results in bloody and nodular splenic masses?
A. Hemangiosarcoma 
B. Infarct
C. Hematoma
D. A, B, C
E. A, C
A

D. A,B,C

86
Q 
Which of the following diseases can result in generalized splenomegaly? 
A. Histoplasmosis
B. Septicemic salmonellosis 
C. Lymphoma
D. A, B, C
E. A, C
A

D. A, B, C

87
Q

Which of the following respiratory diseases is irreversible?
A. Alveolar edema
B. Alveolar emphysema C. Atelectasis
D. Interstitial emphysema E. Erosive bronchitis

A

B. Alveolar emphysema

88
Q

All of the following commonly characterize bronchopneumonia EXCEPT:
A. Cranioventral distribution in the lungs
B. Characterized by alveolar and bronchiolar aggregates of
inflammatory cells including neutrophils
C. Sometimes accompanied by fibrinous pleuritis in cattle
D. Early response to acute respiratory viral infection
E. Response to injury via aspirated material and airway delivery of
bacteria

A

D. Early response to acute respiratory viral infection

89
Q 
Which of the following infectious agents is the most common cause of diffuse interstitial pneumonia in cats?
A. Feline panleukopenia virus
B. Pasteurella multocida
C. Toxoplasma gondii
D. Feline herpesvirus
E. Feline calicivirus
A

C. Toxoplasma gondii

90
Q

Canine distemper virus infection is characterized by all of the following EXCEPT:
A. Intracytoplasmic viral inclusions in lung airway and alveolar epithelial cells
B. Hyperplasia of paracortical lymphocytes in lymph nodes
C. Predisposes dogs to secondary bacterial pneumonia
D. Locally-extensive to diffuse interstitial pneumonia
E. Replication in macrophages

A

B. Hyperplasia of paracortical lymphocytes in lymph nodes

91
Q 
Cattle with obstructive respiratory diseases such as respiratory syncytial virus infection frequently make terminal forced expiratory efforts against obstructed bronchioles and bronchi and develop:
A. Alveolar edema
B. Bronchopneumonia
C. Alveolar emphysema 
D. Interstitial pneumonia 
E. Interstitial emphysema
A

E. Interstitial emphysema

92
Q 
Chronic bacterial bronchitis is characterized by which of the following?
A. Neutrophil-rich inflammatory exudate
B. Dilation of bronchial diameter
C. Bronchial wall fibrosis
D. A, B
E. A, B, C
A

E. A, B, C

93
Q

All of the following often result in generalized (diffuse) splenomegaly EXCEPT?

a. Histoplasmosis
b. Septicemic salmonellosis
c. Lymphoma
d. Hemangiosarcoma
e. Congestion

A

d. Hemangiosarcoma

94
Q

All of the following forms of lung lesions are reversible EXCEPT?

a. Alveolar emphysema
b. Alveolar edema
c. Bronchiectasis
d. Compressive atelectasis
e. A and C

A

e. A and C

95
Q

Which of the following function as stem cells for epithelial repair in pulmonary alveoli?

a. Mucous cells
b. Nonciliated bronchiolar epithelial cells
c. Basal cells
d. Type 1 alveolar epithelial cells
e. Type 2 alveolar epithelial cells

A

e. Type 2 alveolar epithelial cells

96
Q

Which of the following contain toxins activated by ruminal microflora and/or pulmonary cytochrome P450 monoxygenase that can induce interstitial pneumonia in cattle?

a. Purple mint (Perilla mint)
b. Mold damaged sweet potatoes
c. Feed containing L‐tryptophan
d. A, B
e. A,B,C

A

e. A,B,C

97
Q

Which of the following diseases or infections can result in generalized lymphadenomegaly?

a. Multicentric lymphoma
b. Malignant catarrhal fever
c. Feline immunodeficiency virus
d. A, B
e. A, B, C

A

e. A, B, C

Systemic Pathology 2018 (12 decks)

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