ok Flashcards
What kinase does CCK increase the secretion of?
Enterokinase
In what conditions does cck have maximal effect?
Normal vagal tone and the prescence of secretin
What does CCK do in relation to the gall bladder?
Gallbladder contraction, emptying
of the gallbladder and relaxation of
the sphincter of Oddi
What does secretin do in realtion with the spintchers and secretion?
May stimulate the contraction of the pyloric spintcher
Inhibts the secretion of HCL and gastric motility
What does secretin do in relation with CCK
Augments its action on the pancreas and antagonises gastrin
What does secretin do in relation with bicarbonate?
Stimulates its secretion from the pancreatic duct cells and biliary tract
What stimulates secretin secretion?
Stimuli for release
- Acid in duodenum and jejunum (pH <4.5)
(small amounts can be released fromileum)
- Fatty acids
What does secritin do in relation to pepsin?
Stimulates pepsin secretion
Where is GIP released from and what stimulates its release?
- Released from K-cells of duodenum and proximal jejunum
- All major foodstuffs—fat must be hydrolyzed.
- Oral glucose but not i.v. glucose
What does GIP stimulate the release of and what does it inhibit?
Stimulates the release of insulin and inhibits gastrin (Enterogasrone)
