Odontogenic Tumors Flashcards
sources of tumor cells in ameloblastoma
may originate from dental lamina dura, developing enamel organ, odontogenic cyst lining, alveolar mucosa
different types of ameloblastoma
- solid / mutlicystic / convenitonal
- unicystic
- demoplastic
- peripheral ameloblastoma
most common location of ameloblastoma
posteiror mandible
clinical features of ameloblastoma
asymtomatic, often discovered on routine radiographs
as tumors grow, painless enlargement may be noted
radiographic features of ameloblastoma
- unilocular radiolucency, especially early lesions that often progress to multilocular (soap bubble)
- may be associated with impacted tooth
- cortical expansion and thinning
two most common histological variants of ameloblastoma
follicular
plexiform
follicular ameloblastoma
islands of adontogenic epitehlium
plexiform ameloblastoma
interconnected strands of eptihlium
peripheral cells
resemble ameoloblasts (columnar with palisaded nuclei away form basement membrane, reverse nuclear polarity)
central cells
dendritic extensions that interdigitate, resemble stellate reticulum
treatment of ameloblastoma
complete surgical incision
treatment of larger lesions ameloblastoma
en bloc or segmental resection
treatment of smaller ameloblastoma lesions
aggressive curittage
liquid nitrogen
prognosis of ameloblastoma
depends on tumor size, extent, locaiton
maxillary tumors may extend into sinonasal cavity and beyond
recurrence potential of ameloblastoma
recurrence varies with type of treatment, lesion length of follow up
demographic of calcifying epitehlial odontogenic tumor
20-60 years (mean 40)
clinical featores of CEOT
slow growing painless swelling
often associated with impacted tooth, third molar
radiographic features of CEOT
radiolucent, with or without driven snow radiopacities
uni / multilocular
microscopic features of CEOT
islands and sheets of polyhedral cells with abundant eosinophilic cytoplasm, sharply defined cytoplasmic borders and well developed intercellular bridge
variable pleomorphism of cell and nculei (giant nuclei) but without mitotic figures
stain techniqeu used to detect presence of amyloid in tumors
congo red