Ocular Anti-histamines

Question 1

Name the five Ocular antihistamines and indicate which ones are most commonly used (**).

Answer 1

Emedastine difumarate

Epinastine HCL

Alcaftadine

Azelastine**

Ketotifen fumarate ** (Edith’s Evil Allergy Almost Killed her)

Question 2

Which receptors do ocular antihistamine bind to as antagonist?

Answer 2

H1 receptor

Question 3

What indication do ocular antihistamines treat and what ADRs do they cause?

Answer 3

Indications: Allergic conjunctivitis

Adverse reactions: Eye irritation, burning/stinging, redness, pruritis