Ear Drugs

Question 1

What are cerumenolytics and how do they work?

Answer 1

Cerumenolytics are drugs that hydrate and fragment cerumen in the water based form and softens cerumen in oil based form.

Question 2

What is the MOA for Carbamide perioxide 6.5% (OTC)?

Answer 2

Releases peroxide and softens impacted cerumen due to foaming action

Question 3

How do you dose ear medications?

Answer 3

Lie down on side
Place 5 – 10 drops in ear 
Keep applicator tip out of ear
Remain lying on side for 5 minutes or use cotton to keep solution in ear
Can rinse with tepid water after

Question 4

What is the contraindication for Carbamide peroxide 6.5%?

Answer 4

tympanum perforation

Question 5

What drug is used to treat antibacterial/antifungal ear infections?

Answer 5

Acetic Acid Otic Solution 2%
Contains propylene glycol, benzethonium chloride
Indication: Superficial infections of external auditory canal
Contraindication: Perforated TM
AE: Stinging, burning

Question 6

What drug is used to treat an acute otits externa caused by Ps. aeru or Staph aureus?

Answer 6

Finafloxacin (Xtoro)

a suspension

Question 7

What are the ADRs for Fina floxacin?

Answer 7

Pruritus

Nausea