Obstetrics - Disorders of early pregnancy Flashcards
Ectopic pregnancy sites
Tubal ampulla - Most common
Tubal isthmus - Most dangerous
ACID = Ampulla Common Isthmus Dangerous
Ovary
Cervix
Peritoneum
Ectopic pregnancy aetiology
Anything slowing ovum passage to uterus - PIPES
Previous ectopic IVF POCP Endometriosis Surgery
Ectopic pregnancy presentation
Acute abdo pain in woman of child bearing age
= ECTOPIC UNTIL PROVEN OTHERWISE
- Amenorrhoea - 6-8 weeks
- Unilateral abdo pain
- PV bleed - Dark brown
Cervical excitation
Shoulder tip pain
Vomiting
Rupture - Shock + hypo
Ectopic pregnancy investigations
Pregnancy test
b-hCG > 1500 = ECTOPIC
USS
Laparoscopy
Serial serum hCG
Rise > 66% / 48 hours = IUP
Falling / rising slowly = ECTOPIC
Ectopic pregnancy expectant management
Indications
- < 30mm
- Asymptomatic
- Non-rupture
- hCG < 200
- No heartbeat
Serial serum hCG until repeated fall
Ectopic pregnancy medical management
Indications
- < 35mm
- Asymptomatic
- Non-rupture
- hCG < 1500
- No heartbeat
Monitor serum hCG
IM METHOTREXATE
Ectopic pregnancy surgical management
Indications
- > 35mm
- Symptomatic
- Rupture
- hCG > 1500
- Visible heartbeat
Salpingo-oophorECTOMY
Salpingo-oophorOTOMY
Miscarriage definition
Loss of pregnancy < 24 weeks
Miscarriage aetiology
Chromosomal abnormality - Most common
Infection - LATE
Previous miscarriage
DM
Thyroid disease
RFs
- Smoking
- Obesity
- Alcohol
- Maternal age ^
Recurrent miscarriages aetiology
Anti-phospholipid syndrome - Most common
Bleeding disorder
Autoimmune disease
Infection
Smoking
Types of miscarriage
Threatened Inevitable Delayed / missed Incomplete Complete
Threatened miscarriage
Foetus alive
Painless PV bleed
Cervical os CLOSED
Inevitable miscarriage
Foetus alive - But will become complete
Painful bleed
Cervical os OPEN
Delayed / missed miscarriage
Foetus dead
Empty gestational sac
Cervical os CLOSED
Incomplete miscarriage
Foetus dead
Painful PV bleed - Passage of products
Cervical os OPEN
Large uterus
Complete miscarriage
Foetus dead
Large bleed - Passage of products
Cervical os CLOSED
Small uterus
Miscarriages with os open
Inevitable
Incomplete
Miscarriages with os closed
Threatened
Delayed / missed
Complete
Miscarriage investigations
Examine cervical os
hCG
USS
FBC
Cross match
Miscarriage management
Rhesus -ve - Give Anti-D
- Sensitising event!
Stop bleeding - SYNTOMETRINE
Expectant - Wait 7-10 days
Medical
- Mifepristone
- 24-48 hours later - Misoprostol
Surgical
- Manual suction < 13 weeks
- Surgical extraction - ERCP
Abortion act 1967
Legal < 24 weeks
After 24 weeks…
- Continuing would risk maternal life
- Prevent grave injury to mother’s physical/mental health
- Would risk mother’s life more than termination
- Risk to current children
- Child may have severe mental/physical handicap